Cytotoxicity of neolignans from Magnolia obovata fruits

Kyeong Hwa Seo; Dae Young Lee; Rak Hun Jeong; Ki Hyun Yoo; In Sik Chung; Geum Soog Kim; Woo Duck Seo; Hee Cheol Kang; Eun Mi Ahn; Nam In Baek

doi:10.3839/jabc.2013.028

Cytotoxicity of neolignans from Magnolia obovata fruits

Kyeong Hwa Seo
, Dae Young Lee
, Rak Hun Jeong
, Ki Hyun Yoo
, In Sik Chung
, Geum Soog Kim
, Woo Duck Seo
, Hee Cheol Kang
, Eun Mi Ahn
, Nam In Baek

School of Life Science and Biotechnology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Repeated SiO ₂ and octadecyl silica gel (ODS) column chromatographies of the EtOAc fraction from Magnolia obovata fruits, 10 neolignans, named magnolol (1), honokiol (2), isoobovatol (3), isomagnolol (4), obovatol (5), obovatal (6), 9- methoxyobovatol (7), magnobovatol (8), obovaaldehyde (9), and 2-hydroxyobovaaldehyde (10) were isolated and identified. All isolated compounds were evaluated for in vitro cytotoxicity against seven human cancer cell lines.

Original language	English
Pages (from-to)	179-181
Number of pages	3
Journal	Journal of Applied Biological Chemistry
Volume	56
Issue number	3
DOIs	https://doi.org/10.3839/jabc.2013.028
State	Published - 2013

Keywords

Cancer cell
Cytotoxicity
Honokiol
Magnolia obovata
Magnolol
Neolignan

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3839/jabc.2013.028

Cite this

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title = "Cytotoxicity of neolignans from Magnolia obovata fruits",

abstract = " Repeated SiO 2 and octadecyl silica gel (ODS) column chromatographies of the EtOAc fraction from Magnolia obovata fruits, 10 neolignans, named magnolol (1), honokiol (2), isoobovatol (3), isomagnolol (4), obovatol (5), obovatal (6), 9- methoxyobovatol (7), magnobovatol (8), obovaaldehyde (9), and 2-hydroxyobovaaldehyde (10) were isolated and identified. All isolated compounds were evaluated for in vitro cytotoxicity against seven human cancer cell lines.",

keywords = "Cancer cell, Cytotoxicity, Honokiol, Magnolia obovata, Magnolol, Neolignan",

author = "Seo, \{Kyeong Hwa\} and Lee, \{Dae Young\} and Jeong, \{Rak Hun\} and Yoo, \{Ki Hyun\} and Chung, \{In Sik\} and Kim, \{Geum Soog\} and Seo, \{Woo Duck\} and Kang, \{Hee Cheol\} and Ahn, \{Eun Mi\} and Baek, \{Nam In\}",

year = "2013",

doi = "10.3839/jabc.2013.028",

language = "English",

volume = "56",

pages = "179--181",

journal = "Journal of Applied Biological Chemistry",

issn = "1976-0442",

publisher = "Korean Society for Applied Biological Chemistry",

number = "3",

}

TY - JOUR

T1 - Cytotoxicity of neolignans from Magnolia obovata fruits

AU - Seo, Kyeong Hwa

AU - Lee, Dae Young

AU - Jeong, Rak Hun

AU - Yoo, Ki Hyun

AU - Chung, In Sik

AU - Kim, Geum Soog

AU - Seo, Woo Duck

AU - Kang, Hee Cheol

AU - Ahn, Eun Mi

AU - Baek, Nam In

PY - 2013

Y1 - 2013

N2 - Repeated SiO 2 and octadecyl silica gel (ODS) column chromatographies of the EtOAc fraction from Magnolia obovata fruits, 10 neolignans, named magnolol (1), honokiol (2), isoobovatol (3), isomagnolol (4), obovatol (5), obovatal (6), 9- methoxyobovatol (7), magnobovatol (8), obovaaldehyde (9), and 2-hydroxyobovaaldehyde (10) were isolated and identified. All isolated compounds were evaluated for in vitro cytotoxicity against seven human cancer cell lines.

AB - Repeated SiO 2 and octadecyl silica gel (ODS) column chromatographies of the EtOAc fraction from Magnolia obovata fruits, 10 neolignans, named magnolol (1), honokiol (2), isoobovatol (3), isomagnolol (4), obovatol (5), obovatal (6), 9- methoxyobovatol (7), magnobovatol (8), obovaaldehyde (9), and 2-hydroxyobovaaldehyde (10) were isolated and identified. All isolated compounds were evaluated for in vitro cytotoxicity against seven human cancer cell lines.

KW - Cancer cell

KW - Cytotoxicity

KW - Honokiol

KW - Magnolia obovata

KW - Magnolol

KW - Neolignan

UR - https://www.scopus.com/pages/publications/84940356484

U2 - 10.3839/jabc.2013.028

DO - 10.3839/jabc.2013.028

M3 - Article

AN - SCOPUS:84940356484

SN - 1976-0442

VL - 56

SP - 179

EP - 181

JO - Journal of Applied Biological Chemistry

JF - Journal of Applied Biological Chemistry

IS - 3

ER -

Cytotoxicity of neolignans from Magnolia obovata fruits

Abstract

Keywords

UN SDGs

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