Dataset on the changes of neutrophils treated with retinoic acid

Sanjeeb Shrestha, Shin Yeong Kim, Young Jin Yun, Jun Kyu Kim, Jae Man Lee, Minsang Shin, Dong Keun Song, Chang Won Hong

Research output: Contribution to journalArticlepeer-review

Abstract

The data presented in this article are related to the research article entitled “Retinoic acid induces hypersegmentation and enhances cytotoxicity of neutrophils against cancer cells” (S. Shrestha, S.Y. Kim, Y.J. Young, J.K. Kim, J.M. Lee, M. Shin, D.K. Song, C.W. Hong, 2017) [1]. This article complements the potential of retinoic acid to induce changes in effector function of human neutrophils. Here the datasets describe the rate of apoptosis, changes in numbers of nuclear lobes, and the expressions of surface markers in human neutrophils in presence or absence of retinoic acid. The tumor growth in recipient mice with adoptive transfer of retinoic acid-treated neutrophils was evaluated. The included data is made publicly available to criticism and extended analysis.

Original languageEnglish
Pages (from-to)97-102
Number of pages6
JournalData in Brief
Volume12
DOIs
StatePublished - 1 Jun 2017

Keywords

  • Hypersegmentation
  • Neutrophil
  • Phenotype
  • Retinoic acid

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