Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

Kyung Seop Ahn; Woong Seop Sim; In Kuk Lee; Young Bae Seu; Ik Hwan Kim

doi:10.1055/s-2006-957701

Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

Kyung Seop Ahn, Woong Seop Sim, In Kuk Lee, Young Bae Seu, Ik Hwan Kim

School of Life Science and Biotechnology

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Abstract

A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, ¹H-NMR, and ¹³C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.

Original language	English
Pages (from-to)	360-361
Number of pages	2
Journal	Planta Medica
Volume	63
Issue number	4
DOIs	https://doi.org/10.1055/s-2006-957701
State	Published - 1997

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title = "Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigas",

abstract = "A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.",

author = "Ahn, \{Kyung Seop\} and Sim, \{Woong Seop\} and Lee, \{In Kuk\} and Seu, \{Young Bae\} and Kim, \{Ik Hwan\}",

year = "1997",

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language = "English",

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pages = "360--361",

journal = "Planta Medica",

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T2 - A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

AU - Ahn, Kyung Seop

AU - Sim, Woong Seop

AU - Lee, In Kuk

AU - Seu, Young Bae

AU - Kim, Ik Hwan

PY - 1997

Y1 - 1997

N2 - A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.

AB - A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum. Decursinol angelate showed in vitro cytotoxicity and protein kinase C activating activities like decursin.

UR - https://www.scopus.com/pages/publications/0030873779

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DO - 10.1055/s-2006-957701

M3 - Article

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JF - Planta Medica

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ER -

Decursinol angelate: A cytotoxic and protein kinase C activating agent from the root of Angelica gigas

Abstract

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