Determination of the bioconcentration of methidathion and phosalone in Zebrafish (Brachydanio rerio)

The study investigated bioconcentration of methidathion and phosalone, one of organophosphorus pesticides and the most common pesticides in Korea, on zebrafish (Brachydanio rerio). The acute toxicity of phosalone was higher than that of methidathion. The BCF values of phosalone were five times higher than those of methidathion, and depuration rate of methidathion was faster than that of phosalone. Only methidathion had been banned in some countries to use in agriculture areas because methidathion is known as highly toxic compound while phosalone is considered to have moderate toxicity. The results, however, of the study showed that phosalone has stronger bioconcentration effects and acute toxicity than methidathion did. Therefore, the policy for proper managements of phosalone should be urgently established.