Dipicolinic acid-based disk methods for detection of metallo-β-lactamase-producing Pseudomonas spp. and Acinetobacter spp.

Kyeong Seob Shin; Bo Ra Son; Seung Bok Hong; Jungmin Kim

doi:10.1016/j.diagmicrobio.2008.04.015

Dipicolinic acid-based disk methods for detection of metallo-β-lactamase-producing Pseudomonas spp. and Acinetobacter spp.

Kyeong Seob Shin
, Bo Ra Son
, Seung Bok Hong
, Jungmin Kim

Department of Medicine

Chungbuk National University
Juseong University

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

We evaluated novel and simple dipicolinic acid (DPA)-based phenotypic screening methods to detect metallo-β-lactamase (MBL)-producing isolates: DPA disk synergy tests and DPA-based disk tests (DPA-imipenem, DPA-meropenem, or DPA-ceftazidime disk tests). Upon testing these methods on 79 MBL-producing and 95 MBL-nonproducing isolates of Pseudomonas spp. and Acinetobacter spp., their specificity and sensitivity were superior or comparable with those of the EDTA-based phenotypic screening methods.

Original language	English
Pages (from-to)	102-105
Number of pages	4
Journal	Diagnostic Microbiology and Infectious Disease
Volume	62
Issue number	1
DOIs	https://doi.org/10.1016/j.diagmicrobio.2008.04.015
State	Published - Sep 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Dipicolinic acid
Disk synergy test
EDTA
Metallo-β-lactamase

Access to Document

10.1016/j.diagmicrobio.2008.04.015

Cite this

@article{87c5f2855e9a4c77857f7f347c051891,

title = "Dipicolinic acid-based disk methods for detection of metallo-β-lactamase-producing Pseudomonas spp. and Acinetobacter spp.",

abstract = "We evaluated novel and simple dipicolinic acid (DPA)-based phenotypic screening methods to detect metallo-β-lactamase (MBL)-producing isolates: DPA disk synergy tests and DPA-based disk tests (DPA-imipenem, DPA-meropenem, or DPA-ceftazidime disk tests). Upon testing these methods on 79 MBL-producing and 95 MBL-nonproducing isolates of Pseudomonas spp. and Acinetobacter spp., their specificity and sensitivity were superior or comparable with those of the EDTA-based phenotypic screening methods.",

keywords = "Dipicolinic acid, Disk synergy test, EDTA, Metallo-β-lactamase",

author = "Shin, \{Kyeong Seob\} and Son, \{Bo Ra\} and Hong, \{Seung Bok\} and Jungmin Kim",

year = "2008",

month = sep,

doi = "10.1016/j.diagmicrobio.2008.04.015",

language = "English",

volume = "62",

pages = "102--105",

journal = "Diagnostic Microbiology and Infectious Disease",

issn = "0732-8893",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Dipicolinic acid-based disk methods for detection of metallo-β-lactamase-producing Pseudomonas spp. and Acinetobacter spp.

AU - Shin, Kyeong Seob

AU - Son, Bo Ra

AU - Hong, Seung Bok

AU - Kim, Jungmin

PY - 2008/9

Y1 - 2008/9

N2 - We evaluated novel and simple dipicolinic acid (DPA)-based phenotypic screening methods to detect metallo-β-lactamase (MBL)-producing isolates: DPA disk synergy tests and DPA-based disk tests (DPA-imipenem, DPA-meropenem, or DPA-ceftazidime disk tests). Upon testing these methods on 79 MBL-producing and 95 MBL-nonproducing isolates of Pseudomonas spp. and Acinetobacter spp., their specificity and sensitivity were superior or comparable with those of the EDTA-based phenotypic screening methods.

AB - We evaluated novel and simple dipicolinic acid (DPA)-based phenotypic screening methods to detect metallo-β-lactamase (MBL)-producing isolates: DPA disk synergy tests and DPA-based disk tests (DPA-imipenem, DPA-meropenem, or DPA-ceftazidime disk tests). Upon testing these methods on 79 MBL-producing and 95 MBL-nonproducing isolates of Pseudomonas spp. and Acinetobacter spp., their specificity and sensitivity were superior or comparable with those of the EDTA-based phenotypic screening methods.

KW - Dipicolinic acid

KW - Disk synergy test

KW - EDTA

KW - Metallo-β-lactamase

UR - https://www.scopus.com/pages/publications/49549120609

U2 - 10.1016/j.diagmicrobio.2008.04.015

DO - 10.1016/j.diagmicrobio.2008.04.015

M3 - Article

C2 - 18550317

AN - SCOPUS:49549120609

SN - 0732-8893

VL - 62

SP - 102

EP - 105

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 1

ER -

Dipicolinic acid-based disk methods for detection of metallo-β-lactamase-producing Pseudomonas spp. and Acinetobacter spp.

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this