Discoid lupus erythematosus (DLE) in a spitz dog

Moon Jung Goo, Jin Kyu Park, Il Hwa Hong, Hai Jie Yang, Dong Wei Yuan, Mi Ran Ki, Jung Youn Han, Ae Ri Ji, Tae Hwan Kim, Bruce H. Williams, Kyu Shik Jeong

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

A 3-year-old, female Spitz, was presented due to lack of response to therapies with a 6-month history of skin lesions characterized by diffuse erythema and scaling on the dorsal trunk. Physical examination revealed the dog was active and healthy. Skin culture isolated no fungus. Histological examination of skin biopsy specimens revealed interface dermatitis with hydropic degeneration of the basal layers, predominant plasmacytic perivascular accumulation in the dermis, and intensive plasma cell-rich interface mural folliculitis. Moderate CD3-positive lymphocytes infiltrated the superficial dermis. This report may provide unique information of canine discoid lupus erythematosus in an unusual breed with atypical cutaneous lesions.

Original languageEnglish
Pages (from-to)633-635
Number of pages3
JournalJournal of Veterinary Medical Science
Volume70
Issue number6
DOIs
StatePublished - Jun 2008

Keywords

  • Cutaneous lupus erythematosus
  • Interface dermatitis
  • Interface mural folliculitis

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