Abstract
Since the sequencing of the fi rst archaeal genome a decade ago, much attention has been focused on the study of the mechanism of DNA replication of these unique microorganisms. These studies revealed that although many of the archaeal DNA replication proteins are more similar to those of eukarya than bacteria, they are not simply “mini eukarya” but are rather a mosaic of the eukaryal and bacterial systems, with archaeal-specifi c features. Here our current understanding of the process of initiation of DNA replication and its interplay with chromatin and the cell cycle is summarized.
| Original language | English |
|---|---|
| Title of host publication | Thermophiles |
| Subtitle of host publication | Biology and Technology at High Temperatures |
| Publisher | CRC Press |
| Pages | 265-277 |
| Number of pages | 13 |
| ISBN (Electronic) | 9781420008852 |
| ISBN (Print) | 9780849392146 |
| DOIs | |
| State | Published - 1 Jan 2007 |