TY - CHAP
T1 - Early Identification of Psychiatric Disorders
AU - Lee, Tae Young
AU - Kim, Minah
AU - Kwon, Jun Soo
N1 - Publisher Copyright:
© Springer Nature Singapore Pte Ltd. 2019.
PY - 2019
Y1 - 2019
N2 - Early detection and early intervention approach targets people at-risk stages who are very close to conversion to illness, or patients who have just transited the illness stage and have not, yet, become chronic. Rigorous efforts have been put in for early detection and early intervention in psychiatry. A high-risk population is identified by clinical manifestations that, as per their severity and suffering, do not yet meet the diagnostic criteria of psychiatric disorders. There have been attempts to break through the existing phenotype-based diagnostic system using biomarkers, but researchers have yet to overcome the heterogeneity of the disease. Nowadays, the clinical staging models in psychosis, bipolar, and depressive disorders have been proposed as a heuristic and a practical alternative to this. This model is evolving to integrate various demographic factors, clinical symptoms, cognitive functions, and biomarkers.
AB - Early detection and early intervention approach targets people at-risk stages who are very close to conversion to illness, or patients who have just transited the illness stage and have not, yet, become chronic. Rigorous efforts have been put in for early detection and early intervention in psychiatry. A high-risk population is identified by clinical manifestations that, as per their severity and suffering, do not yet meet the diagnostic criteria of psychiatric disorders. There have been attempts to break through the existing phenotype-based diagnostic system using biomarkers, but researchers have yet to overcome the heterogeneity of the disease. Nowadays, the clinical staging models in psychosis, bipolar, and depressive disorders have been proposed as a heuristic and a practical alternative to this. This model is evolving to integrate various demographic factors, clinical symptoms, cognitive functions, and biomarkers.
KW - Biomarkers
KW - Clinical staging
KW - Early identification
KW - Heterogeneity
KW - Psychiatric disorders
UR - http://www.scopus.com/inward/record.url?scp=85074720404&partnerID=8YFLogxK
U2 - 10.1007/978-981-32-9721-0_18
DO - 10.1007/978-981-32-9721-0_18
M3 - Chapter
C2 - 31705504
AN - SCOPUS:85074720404
T3 - Advances in Experimental Medicine and Biology
SP - 341
EP - 352
BT - Advances in Experimental Medicine and Biology
PB - Springer New York LLC
ER -