Effect of atmospheric plasma treatment to titanium surface on initial osteoblast-like cell spreading

In Hye Kim, Jun Sik Son, Tae Yub Kwon, Kyo Han Kim

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Plasma treatments are becoming a popular method for modifying the characteristics of a range of substrate surfaces. Atmospheric pressure plasma is cost-efficient, safe and simple compared to high-pressure plasma. This study examined the effects of atmospheric pressure plasma to a titanium (Ti) surface on osteoblast-like cell (osteoblast) spreading and cellular networks. The characteristics of the Ti surface before and after the atmospheric plasma treatment were analyzed by X-ray photoemission spectroscopy (XPS), scanning electron microscopy (SEM), contact angle measurements, and an optical 3D profiling system. The morphology of osteoblasts attached to the Ti surfaces was observed by SEM and confocal laser scanning microscopy. The atmospheric pressure plasma made the Ti surfaces more hydrophilic. The osteoblasts that adhered to the untreated surface were round and spherical, whereas the cells covered a larger surface area on the plasmatreated surface. The plasma-treated Ti surface showed enhanced cell spreading and migration with more developed cellular networks. In conclusion, an atmospheric plasma treatment is a potential surface modifying method that can enhance the initial the cell affinity at the early stages in vitro.

Original languageEnglish
Pages (from-to)134-137
Number of pages4
JournalJournal of Nanoscience and Nanotechnology
Volume15
Issue number1
DOIs
StatePublished - 1 Jan 2015

Keywords

  • Atmospheric plasma
  • Osteoblast
  • Surface modification
  • Titanium

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