Abstract
Anti-diabetic effects of wild Korean ginseng extracts on multiple low-dose streptozotocin (STZ)-induced diabetic rats were investigated. Rats were administered extracts at rates of 100, 200, and 300 mg/kg of body weight for 8 weeks. Body weight was significantly (p<0.05) lower in ginseng untreated diabetic rats than in ginseng treated rats in spite of significantly (p<0.05) higher food and water intake than for ginseng treated rats. Blood glucose levels were significantly (p<0.05) higher but plasma insulin levels were significantly (p<0.05) lower in 200 and 300 mg/kg of body weight ginseng treated diabetic rats than in rats treated with 100 mg of ginseng and in untreated control rats. The plasma aspartate aminotransaminase level was not significantly (p>0.05) affected; however alanine aminotransaminase and alkaline phosphatase levels were reduced significantly (p<0.05) in higher ginseng dosage rat groups. Anti-diabetic effects were elicited by administration of wild Korean ginseng extracts in multiple low-dose STZ-induced diabetic rats.
| Original language | English |
|---|---|
| Pages (from-to) | 1505-1511 |
| Number of pages | 7 |
| Journal | Food Science and Biotechnology |
| Volume | 24 |
| Issue number | 4 |
| DOIs | |
| State | Published - 3 Aug 2015 |
Keywords
- blood glucose
- serum lipid
- streptozotocin-induced diabetic rat
- wild Korean ginseng
