Effects of biodegradable triblock copolymers on the microencapsulation of ascorbic acid-2-glucoside in W1/O/W2 multi-emulsions

Heui Kyoung Cho; Jin Hun Cho; In Woo Cheong

doi:10.1002/masy.200750316

Effects of biodegradable triblock copolymers on the microencapsulation of ascorbic acid-2-glucoside in W₁/O/W₂ multi-emulsions

Heui Kyoung Cho, Jin Hun Cho, In Woo Cheong

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A skin-active functional material, AA2G (ascorbic acid-2-glucoside, W1 phase), was encapsulated via a stepwise emulsification method using PEO-PLGA-PEO and PEO-PCL-PEO biodegradable triblock copolymers as wall materials. The emulsion stability of the W₁/O/W₂ multi-emulsions was observed using a ferroxyl test method and on-line turbidity analysis for a short period of time. The morphology of the multi-emulsions was observed using the laser confocal and optical microscopes. The use of copolymers in W₁ phase was found to be more effective. The copolymers decreased the size of the multi-emulsions and enhanced emulsion stability.

Original language	English
Pages (from-to)	96-102
Number of pages	7
Journal	Macromolecular Symposia
Volume	249-250
DOIs	https://doi.org/10.1002/masy.200750316
State	Published - 2007

Keywords

Ascorbic acid-2-glucoside
Biodegradable
Emulsion stability
Microencapsulation
Triblock copolymers

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10.1002/masy.200750316

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title = "Effects of biodegradable triblock copolymers on the microencapsulation of ascorbic acid-2-glucoside in W1/O/W2 multi-emulsions",

abstract = "A skin-active functional material, AA2G (ascorbic acid-2-glucoside, W1 phase), was encapsulated via a stepwise emulsification method using PEO-PLGA-PEO and PEO-PCL-PEO biodegradable triblock copolymers as wall materials. The emulsion stability of the W1/O/W2 multi-emulsions was observed using a ferroxyl test method and on-line turbidity analysis for a short period of time. The morphology of the multi-emulsions was observed using the laser confocal and optical microscopes. The use of copolymers in W1 phase was found to be more effective. The copolymers decreased the size of the multi-emulsions and enhanced emulsion stability.",

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T1 - Effects of biodegradable triblock copolymers on the microencapsulation of ascorbic acid-2-glucoside in W1/O/W2 multi-emulsions

AU - Cho, Heui Kyoung

AU - Cho, Jin Hun

AU - Cheong, In Woo

PY - 2007

Y1 - 2007

N2 - A skin-active functional material, AA2G (ascorbic acid-2-glucoside, W1 phase), was encapsulated via a stepwise emulsification method using PEO-PLGA-PEO and PEO-PCL-PEO biodegradable triblock copolymers as wall materials. The emulsion stability of the W1/O/W2 multi-emulsions was observed using a ferroxyl test method and on-line turbidity analysis for a short period of time. The morphology of the multi-emulsions was observed using the laser confocal and optical microscopes. The use of copolymers in W1 phase was found to be more effective. The copolymers decreased the size of the multi-emulsions and enhanced emulsion stability.

AB - A skin-active functional material, AA2G (ascorbic acid-2-glucoside, W1 phase), was encapsulated via a stepwise emulsification method using PEO-PLGA-PEO and PEO-PCL-PEO biodegradable triblock copolymers as wall materials. The emulsion stability of the W1/O/W2 multi-emulsions was observed using a ferroxyl test method and on-line turbidity analysis for a short period of time. The morphology of the multi-emulsions was observed using the laser confocal and optical microscopes. The use of copolymers in W1 phase was found to be more effective. The copolymers decreased the size of the multi-emulsions and enhanced emulsion stability.

KW - Ascorbic acid-2-glucoside

KW - Biodegradable

KW - Emulsion stability

KW - Microencapsulation

KW - Triblock copolymers

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M3 - Article

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SN - 1022-1360

VL - 249-250

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JO - Macromolecular Symposia

JF - Macromolecular Symposia

ER -

Effects of biodegradable triblock copolymers on the microencapsulation of ascorbic acid-2-glucoside in W₁/O/W₂ multi-emulsions

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