Abstract
The same kind of chiral stationary phase with a commercialized chiral column was used to make preparative chiral columns and was applied to resolve racemic N-acetyl-1-naphthylethylamide (3) by preparative liquid chromatography. An improved Chromatographic condition to resolve racemic 3 on the CSP was examined by changing flow rate and kind of the mobile phase and the sample injection volume. The optimized separation conditions were applied to resolve racemic 1,1′-binaphthyl-2,2′-diamine (4).
Original language | English |
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Pages (from-to) | 1336-1340 |
Number of pages | 5 |
Journal | Bulletin of the Korean Chemical Society |
Volume | 25 |
Issue number | 9 |
DOIs | |
State | Published - 20 Sep 2004 |
Keywords
- 1,1′-Binaphthyl-2,2′-diamine
- Chiral separation
- N-Acetyl-1- naphthylethylamide
- Preparative liquid chromatography
- Separation condition