TY - JOUR
T1 - Evaluation of inhibitory potentials of chinese medicinal plants on platelet-activating factor (PAF) receptor binding
AU - Fan, G. J.
AU - Byung Hoon Han, Hoon Han
AU - Kang, Y. H.
AU - Man Ki Park, Ki Park
PY - 2001
Y1 - 2001
N2 - Methanol extracts of eighty Chinese medicinal plants were investigated for platelet-activating factor (PAF) receptor binding inhibitory activity using rabbit platelet. Extracts of Cratoxylon ligustrinum, Kalimeris indica, Euonymus japonica, Ophiopogon japonicus, Gleditsia sinensis, Clausena lansium, Agave sisalana were found to exhibit significant inhibitory effects. Chloroform partition of the Methanol extract of Kalimeris indica was further fractionated by column chromatography to afford one strong active subfraction with 93.6% inhibition at a concentration of 100 μg/ml.
AB - Methanol extracts of eighty Chinese medicinal plants were investigated for platelet-activating factor (PAF) receptor binding inhibitory activity using rabbit platelet. Extracts of Cratoxylon ligustrinum, Kalimeris indica, Euonymus japonica, Ophiopogon japonicus, Gleditsia sinensis, Clausena lansium, Agave sisalana were found to exhibit significant inhibitory effects. Chloroform partition of the Methanol extract of Kalimeris indica was further fractionated by column chromatography to afford one strong active subfraction with 93.6% inhibition at a concentration of 100 μg/ml.
KW - Chinese medicinal plants
KW - Platelet-activating factor (PAF) receptor binding inhibitory activity
UR - http://www.scopus.com/inward/record.url?scp=0035149639&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0035149639
SN - 1226-3907
VL - 7
SP - 33
EP - 37
JO - Natural Product Sciences
JF - Natural Product Sciences
IS - 2
ER -