@inproceedings{8defe110f5ea4e0286246a8881e2702a,
title = "Fabrication of porous poly lactic-co-glycolic acid (PLGA) coated SUS microneedles for improving transdermal drug delivery",
abstract = "This study reports a simple coating method of stainless steel (SUS) microneedles (MNs) with porous PLGA polymer to create uniform porous layer on microneedle in order to provide higher delivery rates. MNs were coated with a thin porous PLGA layer to impart the resultant MNs with high mechanical strength and enhanced delivery rates. Calcein dye was successfully delivered into porcine skin to a depth of 750 μm by the porous-coated MNs, demonstrating that the developed MNs can pierce skin easily. Additionally, lidocaine delivery in phosphate buffered saline (PBS) by porous-coated MNs was increased 25 times than that of non-coated MNs.",
keywords = "Drug delivery, Polymer coating, Porous structure, SUS microneedles",
author = "Asad Ullah and Kim, {Chul Min} and Kim, {Gyu Man}",
note = "Publisher Copyright: {\textcopyright} 17CBMS-0001.; 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 ; Conference date: 22-10-2017 Through 26-10-2017",
year = "2020",
language = "English",
series = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017",
publisher = "Chemical and Biological Microsystems Society",
pages = "348--349",
booktitle = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017",
}