Facile preparation of a hybrid nanoprobe for triple-modality optical/PET/MR imaging

Jeong Chan Park; Mi Kyung Yu; Gwang Il An; Se Il Park; Jungmin Oh; Hong Joo Kim; Joo Hyun Kim; Eun Kyung Wang; Il Hwa Hong; Yeong Su Ha; Tae Hyun Choi; Kyu Shik Jeong; Yongmin Chang; Michael J. Welch; Sangyong Jon; Jeongsoo Yoo

doi:10.1002/smll.201001418

Facile preparation of a hybrid nanoprobe for triple-modality optical/PET/MR imaging

Jeong Chan Park
, Mi Kyung Yu
, Gwang Il An
, Se Il Park
, Jungmin Oh
, Hong Joo Kim
, Joo Hyun Kim
, Eun Kyung Wang
, Il Hwa Hong
, Yeong Su Ha
, Tae Hyun Choi
, Kyu Shik Jeong
, Yongmin Chang
, Michael J. Welch
, Sangyong Jon
, Jeongsoo Yoo

Kyungpook National University
Gwangju Institute of Science and Technology
Korea Institute of Radiological and Medical Sciences
Korea Basic Science Institute
Washington University St. Louis

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

Abstract

A facile method of preparing triple-modality, optical-nuclear-magnetic imaging probes using radiolabeled superparamagnetic nanoparticles is developed. Cerenkov luminescence imaging based on radionuclides showed great potential as a new optical imaging modality. The complementary nature of the optical/PET/MR hybrid nanoprobes facilitated non-invasive differentiation between tumor-metastasized sentinel lymph nodes (SLNs) and tumor-free SLNs.

Original language	English
Pages (from-to)	2863-2868
Number of pages	6
Journal	Small
Volume	6
Issue number	24
DOIs	https://doi.org/10.1002/smll.201001418
State	Published - 20 Dec 2010

Keywords

hybrid materials
imaging agents
multimodality imaging
nanoparticles

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10.1002/smll.201001418

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abstract = "A facile method of preparing triple-modality, optical-nuclear-magnetic imaging probes using radiolabeled superparamagnetic nanoparticles is developed. Cerenkov luminescence imaging based on radionuclides showed great potential as a new optical imaging modality. The complementary nature of the optical/PET/MR hybrid nanoprobes facilitated non-invasive differentiation between tumor-metastasized sentinel lymph nodes (SLNs) and tumor-free SLNs.",

keywords = "hybrid materials, imaging agents, multimodality imaging, nanoparticles",

author = "Park, \{Jeong Chan\} and Yu, \{Mi Kyung\} and An, \{Gwang Il\} and Park, \{Se Il\} and Jungmin Oh and Kim, \{Hong Joo\} and Kim, \{Joo Hyun\} and Wang, \{Eun Kyung\} and Hong, \{Il Hwa\} and Ha, \{Yeong Su\} and Choi, \{Tae Hyun\} and Jeong, \{Kyu Shik\} and Yongmin Chang and Welch, \{Michael J.\} and Sangyong Jon and Jeongsoo Yoo",

year = "2010",

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day = "20",

doi = "10.1002/smll.201001418",

language = "English",

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T1 - Facile preparation of a hybrid nanoprobe for triple-modality optical/PET/MR imaging

AU - Park, Jeong Chan

AU - Yu, Mi Kyung

AU - An, Gwang Il

AU - Park, Se Il

AU - Oh, Jungmin

AU - Kim, Hong Joo

AU - Kim, Joo Hyun

AU - Wang, Eun Kyung

AU - Hong, Il Hwa

AU - Ha, Yeong Su

AU - Choi, Tae Hyun

AU - Jeong, Kyu Shik

AU - Chang, Yongmin

AU - Welch, Michael J.

AU - Jon, Sangyong

AU - Yoo, Jeongsoo

PY - 2010/12/20

Y1 - 2010/12/20

N2 - A facile method of preparing triple-modality, optical-nuclear-magnetic imaging probes using radiolabeled superparamagnetic nanoparticles is developed. Cerenkov luminescence imaging based on radionuclides showed great potential as a new optical imaging modality. The complementary nature of the optical/PET/MR hybrid nanoprobes facilitated non-invasive differentiation between tumor-metastasized sentinel lymph nodes (SLNs) and tumor-free SLNs.

AB - A facile method of preparing triple-modality, optical-nuclear-magnetic imaging probes using radiolabeled superparamagnetic nanoparticles is developed. Cerenkov luminescence imaging based on radionuclides showed great potential as a new optical imaging modality. The complementary nature of the optical/PET/MR hybrid nanoprobes facilitated non-invasive differentiation between tumor-metastasized sentinel lymph nodes (SLNs) and tumor-free SLNs.

KW - hybrid materials

KW - imaging agents

KW - multimodality imaging

KW - nanoparticles

UR - https://www.scopus.com/pages/publications/78650358981

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DO - 10.1002/smll.201001418

M3 - Article

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AN - SCOPUS:78650358981

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SP - 2863

EP - 2868

JO - Small

JF - Small

IS - 24

ER -

Facile preparation of a hybrid nanoprobe for triple-modality optical/PET/MR imaging

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Keywords

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