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Functionalized Surface Coatings for Rigid Contact Lenses

  • Roeya Refaei
  • , Kyueui Lee
  • , Goun Amy Lee
  • , Paul Demian
  • , Fouad El Mansouri
  • , Phillip B. Messersmith
  • , Mouad Lamrani
  • , Mohamed Khaddor
  • , Nabil Allali
    • Abdelmalek Essaâdi University
    • Department of Chemistry and Green-Nano Materials Research Center
    • University of California at Berkeley
    • Menicon Co., Ltd.
    • Geneva branch

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations

    Abstract

    This research evolves into a comparative study of three different phenolic composites as coatings for rigid contact lenses, with a particular emphasis on enhancing their antifouling properties and hydrophobicity. The primary layer, comprised of diverse phenolic compounds, serves as a sturdy foundation. An exclusive secondary layer, featuring synthetic peptoids, is introduced to further minimize biofouling. Validated through X-ray photoelectron spectroscopy, the surface analysis confirms the successful integration of the polyphenolic layers and the subsequent grafting of peptoids onto the lens surface. The efficacy of the proposed coatings is substantiated through protein adsorption tests, providing definitive evidence of their antifouling capabilities. This research employs a nuanced assessment of coating performance, utilizing the quantification of fluorescence intensity to gauge effectiveness. Additionally, contact angle measurements offer insights into wettability and surface characteristics, contributing to a comprehensive understanding of the coating’s practicality.

    Original languageEnglish
    Article number154
    JournalJournal of Functional Biomaterials
    Volume15
    Issue number6
    DOIs
    StatePublished - Jun 2024

    Keywords

    • antifouling
    • coating
    • peptoid
    • polyphenols

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