Abstract
The stress-responsive bioprocess concept has been developed into an environmentally friendly biosensor with low energy consumption and high recovery yield. To improve chitosanase production during Streptomyces griseus cultivation, heat-stress was applied to the bioprocess with monitoring using an on-line gas sensing system. When exposed to heat-stress with liposomes, the chitosanase productivity was 2.6 times greater than for conventional cultivation. The mixed gas components could be distinguished using a principal component analysis during chitosanase production. The online-monitoring system reflected basic changes in growth conditions and metabolite formation in cells. The array type gas-sensing system was capable of detecting bacterial infection faster than conventional sensor systems. The gas sensor system can play a key role in monitoring and controlling stress levels in a stress-responsive bioprocess.
| Original language | English |
|---|---|
| Pages (from-to) | 875-881 |
| Number of pages | 7 |
| Journal | Food Science and Biotechnology |
| Volume | 24 |
| Issue number | 3 |
| DOIs | |
| State | Published - 26 Jun 2015 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 7 Affordable and Clean Energy
Keywords
- chitosanase
- gas-sensing
- heat-responsive
- principal component analysis
- Streptomyces griseus
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