TY - JOUR
T1 - Genetic diversity of porcine circovirus type 2 from pigs in Republic of Korea
AU - Chae, Joon Seok
AU - Choi, Kyoung Seong
PY - 2010/4
Y1 - 2010/4
N2 - Porcine circovirus type 2 (PCV2) is the causative agent of postweaning multisystemic wasting syndrome (PMWS). In this study, 38 PCV2 cases obtained from different pig farms with different health conditions in Republic of Korea were sequenced and analyzed. Phylogenetic analysis showed that our cases had a greater variation and the existence of two PCV2 groups with at least four subgroups (1A, 1C, 2D, and 2E). Most cases obtained from PMWS-affected herds were in group 1, whereas cases with no clinical signs compatible with PMWS (wasted non-PMWS) were included within group 2. Moreover, four cases from the wasted non-PMWS belonged to PCV2-group 1. Therefore, our results suggest that PCV2-group 1 is more related to PMWS than group 2.
AB - Porcine circovirus type 2 (PCV2) is the causative agent of postweaning multisystemic wasting syndrome (PMWS). In this study, 38 PCV2 cases obtained from different pig farms with different health conditions in Republic of Korea were sequenced and analyzed. Phylogenetic analysis showed that our cases had a greater variation and the existence of two PCV2 groups with at least four subgroups (1A, 1C, 2D, and 2E). Most cases obtained from PMWS-affected herds were in group 1, whereas cases with no clinical signs compatible with PMWS (wasted non-PMWS) were included within group 2. Moreover, four cases from the wasted non-PMWS belonged to PCV2-group 1. Therefore, our results suggest that PCV2-group 1 is more related to PMWS than group 2.
KW - PCV2-group 1 and 2
KW - Phylogenetic analysis
KW - Porcine circovirus type 2
KW - Postweaning multisystemic wasting syndrome
UR - http://www.scopus.com/inward/record.url?scp=76849087819&partnerID=8YFLogxK
U2 - 10.1016/j.rvsc.2009.08.003
DO - 10.1016/j.rvsc.2009.08.003
M3 - Article
C2 - 19744683
AN - SCOPUS:76849087819
SN - 0034-5288
VL - 88
SP - 333
EP - 338
JO - Research in Veterinary Science
JF - Research in Veterinary Science
IS - 2
ER -