Abstract
The objective of this study was to evaluate the effectiveness of optical Doppler tomography (ODT) using a portable handheld-type probe for investigating the blood flow in blood vessels of cell carcinoma-affected small animal models. To perform in vivo and real-time investigation, we developed a spectral domain-optical Doppler tomography (SD-ODT) system equipped with a portable handheld-type scanning probe, which uses the Kasai autocorrelation algorithm for Doppler imaging. The system capabilities were evaluated by conducting preliminary experiments on flow measurement in a microtube. The study was performed on healthy and squamous cell carcinoma-affected mouse specimens. The results demonstrate the possibilities and advantages of employing an SD-ODT system with handheld-type scanning probe for cell carcinoma investigation in small animal models.
Original language | English |
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Pages (from-to) | 183-188 |
Number of pages | 6 |
Journal | Infrared Physics and Technology |
Volume | 95 |
DOIs | |
State | Published - Dec 2018 |
Keywords
- Cancer detection
- Doppler measurement
- Optical coherence tomography
- Parallel processing
- Probes