Handheld-probe-based optical Doppler tomography for blood flow imaging

Deokmin Jeon, Naresh Kumar Ravichandran, Unsang Jung, Mansik Jeon, Jeehyun Kim

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The objective of this study was to evaluate the effectiveness of optical Doppler tomography (ODT) using a portable handheld-type probe for investigating the blood flow in blood vessels of cell carcinoma-affected small animal models. To perform in vivo and real-time investigation, we developed a spectral domain-optical Doppler tomography (SD-ODT) system equipped with a portable handheld-type scanning probe, which uses the Kasai autocorrelation algorithm for Doppler imaging. The system capabilities were evaluated by conducting preliminary experiments on flow measurement in a microtube. The study was performed on healthy and squamous cell carcinoma-affected mouse specimens. The results demonstrate the possibilities and advantages of employing an SD-ODT system with handheld-type scanning probe for cell carcinoma investigation in small animal models.

Original languageEnglish
Pages (from-to)183-188
Number of pages6
JournalInfrared Physics and Technology
Volume95
DOIs
StatePublished - Dec 2018

Keywords

  • Cancer detection
  • Doppler measurement
  • Optical coherence tomography
  • Parallel processing
  • Probes

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