Abstract
The objective of this study was to evaluate the effectiveness of optical Doppler tomography (ODT) using a portable handheld-type probe for investigating the blood flow in blood vessels of cell carcinoma-affected small animal models. To perform in vivo and real-time investigation, we developed a spectral domain-optical Doppler tomography (SD-ODT) system equipped with a portable handheld-type scanning probe, which uses the Kasai autocorrelation algorithm for Doppler imaging. The system capabilities were evaluated by conducting preliminary experiments on flow measurement in a microtube. The study was performed on healthy and squamous cell carcinoma-affected mouse specimens. The results demonstrate the possibilities and advantages of employing an SD-ODT system with handheld-type scanning probe for cell carcinoma investigation in small animal models.
| Original language | English |
|---|---|
| Pages (from-to) | 183-188 |
| Number of pages | 6 |
| Journal | Infrared Physics and Technology |
| Volume | 95 |
| DOIs | |
| State | Published - Dec 2018 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancer detection
- Doppler measurement
- Optical coherence tomography
- Parallel processing
- Probes
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