TY - JOUR
T1 - Hematogenous infection of the human temporomandibular joint
AU - Jeon, Hyo Sang
AU - Hong, Sam Pyo
AU - Cho, Byoung Ouck
AU - Mulyukin, Andrey
AU - Choi, Je Yong
AU - Kim, Seong Gon
PY - 2005/2
Y1 - 2005/2
N2 - This study was designed to discover the relationship between bacteremia and the presence of specific bacterial species in the synovial fluid of the human temporomandibular joint (TMJ). Sixteen volunteers (female to male, 1:2.2; average age, 30.00 ± 9.93 years) who received operations via intraoral incision participated in this study. Samples from the blood and TMJ synovial fluid of the patients were taken preoperatively and postoperatively and analyzed by PCR assays with specific primers for the clinically important bacteria Staphylococcus aureus, Streptococcus mitis, and β-hemolytic Streptococcus. PCR-based assays revealed the occurrence of S aureus in 68.8% and 50% of the total blood and synovial fluid samples collected immediately after the operations, which statistically differed from the preoperative samples (P < .05). However, the frequency of the other bacteria, S mitis and β-hemolytic Streptococcus, in pre- and postoperative blood samples had no such a difference (P > .05). The chi-square test showed a significant association between the presence of S aureus in the blood and in TMJ synovial fluid (χ2 = 6.409, P < .05), and the probability of hematogenous infection of the TMJ was estimated as 55.5%. Hence, the data obtained provided evidence that the invasion of S aureus into TMJ synovial fluid was due to the presence of these bacteria in the blood. To our knowledge, this is the first report of the bacteremia-related mechanism of S aureus invasion in the human TMJ.
AB - This study was designed to discover the relationship between bacteremia and the presence of specific bacterial species in the synovial fluid of the human temporomandibular joint (TMJ). Sixteen volunteers (female to male, 1:2.2; average age, 30.00 ± 9.93 years) who received operations via intraoral incision participated in this study. Samples from the blood and TMJ synovial fluid of the patients were taken preoperatively and postoperatively and analyzed by PCR assays with specific primers for the clinically important bacteria Staphylococcus aureus, Streptococcus mitis, and β-hemolytic Streptococcus. PCR-based assays revealed the occurrence of S aureus in 68.8% and 50% of the total blood and synovial fluid samples collected immediately after the operations, which statistically differed from the preoperative samples (P < .05). However, the frequency of the other bacteria, S mitis and β-hemolytic Streptococcus, in pre- and postoperative blood samples had no such a difference (P > .05). The chi-square test showed a significant association between the presence of S aureus in the blood and in TMJ synovial fluid (χ2 = 6.409, P < .05), and the probability of hematogenous infection of the TMJ was estimated as 55.5%. Hence, the data obtained provided evidence that the invasion of S aureus into TMJ synovial fluid was due to the presence of these bacteria in the blood. To our knowledge, this is the first report of the bacteremia-related mechanism of S aureus invasion in the human TMJ.
UR - http://www.scopus.com/inward/record.url?scp=12344319023&partnerID=8YFLogxK
U2 - 10.1016/j.tripleo.2004.11.001
DO - 10.1016/j.tripleo.2004.11.001
M3 - Article
C2 - 15660076
AN - SCOPUS:12344319023
SN - 1079-2104
VL - 99
SP - E11-E17
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
IS - 2
ER -