Hemodynamic investigation on blood flow in a rugged microchannel

C. W. Park; G. M. Kim; S. H. Shin; S. J. Lee; Y. H. Ku; J. H. Jang

doi:10.1117/12.649749

Hemodynamic investigation on blood flow in a rugged microchannel

C. W. Park, G. M. Kim, S. H. Shin, S. J. Lee, Y. H. Ku, J. H. Jang

School of Mechanical Engineering

Research output: Contribution to journal › Conference article › peer-review

Abstract

The biological flow characteristics inside a rugged surface type microchannel are investigated experimentally using a micro-particle image velocimetry (micro-PIV) method. The main objectives of this study are to understand the blood flow structure inside a micro-domain blood vessel and to identify the feasibility of nano-scale fluorescent particles for velocity field measurement in a micron-sized channel. The flow field is analyzed with a spatial resolution of 1K×1K pixels at low Reynolds number flow. To obtain the spatial distributions of mean velocity, 100 instantaneous velocity fields are captured and ensemble-averaged. As a result, for the case of blood flow, there are substantial cell deformation and variations to pass through the rugged surface of a microchannel and the clear velocity vector field was acquired by using the present micro-PIV technique.

Original language	English
Article number	60500Y
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	6050
DOIs	https://doi.org/10.1117/12.649749
State	Published - 2005
Event	Optomechatronic Micro/Nano Devices and Components - Sappora, Japan Duration: 5 Dec 2005 → 7 Dec 2005

Keywords

Blood flow
Deformation
Feasibility
Fluorescent particle
Micro-PIV
Rugged microchannel

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10.1117/12.649749

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title = "Hemodynamic investigation on blood flow in a rugged microchannel",

abstract = "The biological flow characteristics inside a rugged surface type microchannel are investigated experimentally using a micro-particle image velocimetry (micro-PIV) method. The main objectives of this study are to understand the blood flow structure inside a micro-domain blood vessel and to identify the feasibility of nano-scale fluorescent particles for velocity field measurement in a micron-sized channel. The flow field is analyzed with a spatial resolution of 1K×1K pixels at low Reynolds number flow. To obtain the spatial distributions of mean velocity, 100 instantaneous velocity fields are captured and ensemble-averaged. As a result, for the case of blood flow, there are substantial cell deformation and variations to pass through the rugged surface of a microchannel and the clear velocity vector field was acquired by using the present micro-PIV technique.",

keywords = "Blood flow, Deformation, Feasibility, Fluorescent particle, Micro-PIV, Rugged microchannel",

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TY - JOUR

T1 - Hemodynamic investigation on blood flow in a rugged microchannel

AU - Park, C. W.

AU - Kim, G. M.

AU - Shin, S. H.

AU - Lee, S. J.

AU - Ku, Y. H.

AU - Jang, J. H.

PY - 2005

Y1 - 2005

N2 - The biological flow characteristics inside a rugged surface type microchannel are investigated experimentally using a micro-particle image velocimetry (micro-PIV) method. The main objectives of this study are to understand the blood flow structure inside a micro-domain blood vessel and to identify the feasibility of nano-scale fluorescent particles for velocity field measurement in a micron-sized channel. The flow field is analyzed with a spatial resolution of 1K×1K pixels at low Reynolds number flow. To obtain the spatial distributions of mean velocity, 100 instantaneous velocity fields are captured and ensemble-averaged. As a result, for the case of blood flow, there are substantial cell deformation and variations to pass through the rugged surface of a microchannel and the clear velocity vector field was acquired by using the present micro-PIV technique.

AB - The biological flow characteristics inside a rugged surface type microchannel are investigated experimentally using a micro-particle image velocimetry (micro-PIV) method. The main objectives of this study are to understand the blood flow structure inside a micro-domain blood vessel and to identify the feasibility of nano-scale fluorescent particles for velocity field measurement in a micron-sized channel. The flow field is analyzed with a spatial resolution of 1K×1K pixels at low Reynolds number flow. To obtain the spatial distributions of mean velocity, 100 instantaneous velocity fields are captured and ensemble-averaged. As a result, for the case of blood flow, there are substantial cell deformation and variations to pass through the rugged surface of a microchannel and the clear velocity vector field was acquired by using the present micro-PIV technique.

KW - Blood flow

KW - Deformation

KW - Feasibility

KW - Fluorescent particle

KW - Micro-PIV

KW - Rugged microchannel

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JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

M1 - 60500Y

T2 - Optomechatronic Micro/Nano Devices and Components

Y2 - 5 December 2005 through 7 December 2005

ER -

Hemodynamic investigation on blood flow in a rugged microchannel

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Keywords

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