Hemoglobin contrast in magnetomotive optical Doppler tomography

Jeehyun Kim; Junghwan Oh; Thomas E. Milner; J. Stuart Nelson

doi:10.1364/OL.31.000778

Hemoglobin contrast in magnetomotive optical Doppler tomography

Jeehyun Kim, Junghwan Oh, Thomas E. Milner, J. Stuart Nelson

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

We introduce a novel contrast mechanism for imaging blood flow by use of magnetomotive optical Doppler tomography (MM-ODT), which combines an externally applied temporally oscillating high-strength magnetic field with ODT to detect erythrocytes moving according to the field gradient. Hemoglobin contrast was demonstrated in a capillary tube filled with moving blood by imaging the Doppler frequency shift, which was observed independently of blood flow rate and direction. Results suggest that MM-ODT may be a promising technique with which to image blood flow.

Original language	English
Pages (from-to)	778-780
Number of pages	3
Journal	Optics Letters
Volume	31
Issue number	6
DOIs	https://doi.org/10.1364/OL.31.000778
State	Published - 2006

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10.1364/OL.31.000778

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title = "Hemoglobin contrast in magnetomotive optical Doppler tomography",

abstract = "We introduce a novel contrast mechanism for imaging blood flow by use of magnetomotive optical Doppler tomography (MM-ODT), which combines an externally applied temporally oscillating high-strength magnetic field with ODT to detect erythrocytes moving according to the field gradient. Hemoglobin contrast was demonstrated in a capillary tube filled with moving blood by imaging the Doppler frequency shift, which was observed independently of blood flow rate and direction. Results suggest that MM-ODT may be a promising technique with which to image blood flow.",

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AU - Kim, Jeehyun

AU - Oh, Junghwan

AU - Milner, Thomas E.

AU - Nelson, J. Stuart

PY - 2006

Y1 - 2006

N2 - We introduce a novel contrast mechanism for imaging blood flow by use of magnetomotive optical Doppler tomography (MM-ODT), which combines an externally applied temporally oscillating high-strength magnetic field with ODT to detect erythrocytes moving according to the field gradient. Hemoglobin contrast was demonstrated in a capillary tube filled with moving blood by imaging the Doppler frequency shift, which was observed independently of blood flow rate and direction. Results suggest that MM-ODT may be a promising technique with which to image blood flow.

AB - We introduce a novel contrast mechanism for imaging blood flow by use of magnetomotive optical Doppler tomography (MM-ODT), which combines an externally applied temporally oscillating high-strength magnetic field with ODT to detect erythrocytes moving according to the field gradient. Hemoglobin contrast was demonstrated in a capillary tube filled with moving blood by imaging the Doppler frequency shift, which was observed independently of blood flow rate and direction. Results suggest that MM-ODT may be a promising technique with which to image blood flow.

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DO - 10.1364/OL.31.000778

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EP - 780

JO - Optics Letters

JF - Optics Letters

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Hemoglobin contrast in magnetomotive optical Doppler tomography

Abstract

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