Abstract
Heterologous expression of fission yeast Schizosaccharomyces pombe heavy metal tolerance factor 1 (SpHMT1) confers increased tolerance to Cd but sensitivity to Cu in budding yeast. Due to its sensitivity to Cu, SpHMT1 cannot be used in bioremediation of Cd in Cu-contaminated sites. Thus, in the present study we attempted to solve this problem by expressing SpHMT1 in Cu-resistant yeast mutants.
| Original language | English |
|---|---|
| Pages (from-to) | 647-651 |
| Number of pages | 5 |
| Journal | Journal of Applied Biological Chemistry |
| Volume | 53 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2010 |
Keywords
- Bioremediation
- Cadmium
- Copper
- Heavy metal tolerance factor
- Yeast