High-pressure processing of milk alleviates atopic dermatitis in DNCB-induced Balb/c mice

Jieun Lee; Eun Ji Choi; Sun Young Park; Ga Young Jeon; Ja Young Jang; Young Jun Oh; Seul Ki Lim; Min Sung Kwon; Tae Woon Kim; Jong Hee Lee; Hae Woong Park; Hyun Ju Kim; Jong Soo Kang; Jung Tae Jeon; Hak Jong Choi

doi:10.1007/s13594-015-0239-0

High-pressure processing of milk alleviates atopic dermatitis in DNCB-induced Balb/c mice

Jieun Lee, Eun Ji Choi, Sun Young Park, Ga Young Jeon, Ja Young Jang, Young Jun Oh, Seul Ki Lim, Min Sung Kwon, Tae Woon Kim, Jong Hee Lee, Hae Woong Park, Hyun Ju Kim, Jong Soo Kang, Jung Tae Jeon, Hak Jong Choi

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

High pressure (HP) is recognized as the alternative process technology of heat treatment in food production. Although milk was the first food product to be treated with HP, the allergenicity of HP-treated milk remains to be elucidated. Thus, this study was conducted to investigate the effects of HP treatment on the alleviation of atopic dermatitis (AD) caused by milk in a mouse model. To investigate the effect of HP treatment on the alleviation of AD, Balb/c mice were fed HP-treated milk orally for 7 days following induction of AD with 1-chloro-2,4-dinitro-benzene (DNCB). Mice fed with HP-treated milk exhibited markedly lower serum IgE level than DNCB-treated mice. These results suggest that HP may be applicable as an alternative process for the development of hypoallergenic milk products.

Original language	English
Pages (from-to)	67-78
Number of pages	12
Journal	Dairy Science and Technology
Volume	96
Issue number	1
DOIs	https://doi.org/10.1007/s13594-015-0239-0
State	Published - 1 Jan 2016

Keywords

Atopic dermatitis
High pressure
Milk

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s13594-015-0239-0

Cite this

Lee, J., Choi, E. J., Park, S. Y., Jeon, G. Y., Jang, J. Y., Oh, Y. J., Lim, S. K., Kwon, M. S., Kim, T. W., Lee, J. H., Park, H. W., Kim, H. J., Kang, J. S., Jeon, J. T., & Choi, H. J. (2016). High-pressure processing of milk alleviates atopic dermatitis in DNCB-induced Balb/c mice. Dairy Science and Technology, 96(1), 67-78. https://doi.org/10.1007/s13594-015-0239-0

@article{c029c49fd0df4f0c8c5f2ee3d6553a32,

title = "High-pressure processing of milk alleviates atopic dermatitis in DNCB-induced Balb/c mice",

abstract = "High pressure (HP) is recognized as the alternative process technology of heat treatment in food production. Although milk was the first food product to be treated with HP, the allergenicity of HP-treated milk remains to be elucidated. Thus, this study was conducted to investigate the effects of HP treatment on the alleviation of atopic dermatitis (AD) caused by milk in a mouse model. To investigate the effect of HP treatment on the alleviation of AD, Balb/c mice were fed HP-treated milk orally for 7 days following induction of AD with 1-chloro-2,4-dinitro-benzene (DNCB). Mice fed with HP-treated milk exhibited markedly lower serum IgE level than DNCB-treated mice. These results suggest that HP may be applicable as an alternative process for the development of hypoallergenic milk products.",

keywords = "Atopic dermatitis, High pressure, Milk",

author = "Jieun Lee and Choi, {Eun Ji} and Park, {Sun Young} and Jeon, {Ga Young} and Jang, {Ja Young} and Oh, {Young Jun} and Lim, {Seul Ki} and Kwon, {Min Sung} and Kim, {Tae Woon} and Lee, {Jong Hee} and Park, {Hae Woong} and Kim, {Hyun Ju} and Kang, {Jong Soo} and Jeon, {Jung Tae} and Choi, {Hak Jong}",

note = "Publisher Copyright: {\textcopyright} 2015, INRA and Springer-Verlag France.",

year = "2016",

month = jan,

day = "1",

doi = "10.1007/s13594-015-0239-0",

language = "English",

volume = "96",

pages = "67--78",

journal = "Dairy Science and Technology",

issn = "1958-5586",

publisher = "Springer Science + Business Media",

number = "1",

}

TY - JOUR

T1 - High-pressure processing of milk alleviates atopic dermatitis in DNCB-induced Balb/c mice

AU - Lee, Jieun

AU - Choi, Eun Ji

AU - Park, Sun Young

AU - Jeon, Ga Young

AU - Jang, Ja Young

AU - Oh, Young Jun

AU - Lim, Seul Ki

AU - Kwon, Min Sung

AU - Kim, Tae Woon

AU - Lee, Jong Hee

AU - Park, Hae Woong

AU - Kim, Hyun Ju

AU - Kang, Jong Soo

AU - Jeon, Jung Tae

AU - Choi, Hak Jong

PY - 2016/1/1

Y1 - 2016/1/1

N2 - High pressure (HP) is recognized as the alternative process technology of heat treatment in food production. Although milk was the first food product to be treated with HP, the allergenicity of HP-treated milk remains to be elucidated. Thus, this study was conducted to investigate the effects of HP treatment on the alleviation of atopic dermatitis (AD) caused by milk in a mouse model. To investigate the effect of HP treatment on the alleviation of AD, Balb/c mice were fed HP-treated milk orally for 7 days following induction of AD with 1-chloro-2,4-dinitro-benzene (DNCB). Mice fed with HP-treated milk exhibited markedly lower serum IgE level than DNCB-treated mice. These results suggest that HP may be applicable as an alternative process for the development of hypoallergenic milk products.

AB - High pressure (HP) is recognized as the alternative process technology of heat treatment in food production. Although milk was the first food product to be treated with HP, the allergenicity of HP-treated milk remains to be elucidated. Thus, this study was conducted to investigate the effects of HP treatment on the alleviation of atopic dermatitis (AD) caused by milk in a mouse model. To investigate the effect of HP treatment on the alleviation of AD, Balb/c mice were fed HP-treated milk orally for 7 days following induction of AD with 1-chloro-2,4-dinitro-benzene (DNCB). Mice fed with HP-treated milk exhibited markedly lower serum IgE level than DNCB-treated mice. These results suggest that HP may be applicable as an alternative process for the development of hypoallergenic milk products.

KW - Atopic dermatitis

KW - High pressure

KW - Milk

UR - http://www.scopus.com/inward/record.url?scp=84951278475&partnerID=8YFLogxK

U2 - 10.1007/s13594-015-0239-0

DO - 10.1007/s13594-015-0239-0

M3 - Article

AN - SCOPUS:84951278475

SN - 1958-5586

VL - 96

SP - 67

EP - 78

JO - Dairy Science and Technology

JF - Dairy Science and Technology

IS - 1

ER -

High-pressure processing of milk alleviates atopic dermatitis in DNCB-induced Balb/c mice

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Cite this