High-resolution photoacoustic microscopy based on a transparent ultrasonic transducer

Jeongwoo Park, Byullee Park, Chulhong Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We present high-resolution and high-SNR in vivo vascular imaging of the mouse eye, brain, and ear with photoacoustic microscopy (PAM) integrated with a transparent ultrasound transducer. We observed microvessels in a chemically damaged mouse eye. Particularly, the performance of PAM as a comprehensive eye disease diagnosis tool was demonstrated by observing not only corneal neovascularization, but also iris blood vessels and hemorrhages in a cloudy state of the corneal. Second, we delineated in vivo mouse brain vascular imaging at high resolution with a depth encoding. Third, we monitored the ears of tumor-bearing mice to observe for angiogenesis over time.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2022
EditorsAlexander A. Oraevsky, Lihong V. Wang
PublisherSPIE
ISBN (Electronic)9781510647916
DOIs
StatePublished - 2022
EventPhotons Plus Ultrasound: Imaging and Sensing 2022 - Virtual, Online
Duration: 20 Feb 202224 Feb 2022

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11960
ISSN (Print)1605-7422

Conference

ConferencePhotons Plus Ultrasound: Imaging and Sensing 2022
CityVirtual, Online
Period20/02/2224/02/22

Keywords

  • photoacoustic imaging
  • transparent ultrasound transducer

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