Hybrid intelligent methods for microarray data analysis

Ganeshkumar Pugalendhi, Ku Jin Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Data produced out of microarray experiments are of great use for the physician when it is presented in a meaningful manner. This paper proposes hybrid intelligent methods for addressing the challenges in analyzing the microarray data. The concept of fuzzy and rough set is hybridized with FInformation (FRFI) for gene selection. An optimal fuzzy logic based classifier (FLC) is developed for sample classification using a hybrid Genetic Swarm Algorithm (GSA). Detailed experiments are conducted using microarray data related to Cancer and Rheumatoid Arthritis. From the simulation study, it is found that the proposed FRFI-FLC-GSA produces compact classification system with reasonably good informative genes that can be used for disease diagnosis.

Original languageEnglish
Title of host publication2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781467379830
DOIs
StatePublished - 28 Dec 2015
Event15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015 - Belgrade, Serbia
Duration: 2 Nov 20154 Nov 2015

Publication series

Name2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015

Conference

Conference15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015
Country/TerritorySerbia
CityBelgrade
Period2/11/154/11/15

Keywords

  • FInformation
  • Fuzzy-Rough Set
  • Genetic Swarm Algorithm
  • Microarray data

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