@inproceedings{345a8fb4bdfb4426888b8c3719f31044,
title = "Identification of Dementia Related Brain Functional Networks with Minimum Spanning Trees",
abstract = "Neurocognitive impairments such as mild cognitive impairment (MCI), alzheimer's disease (AD) and vascular dementia (VD) effect the functional connectivity across the brain networks that aid proper neurocognitive functioning. Identification of dementia related disorders has remained a challenge due to their overlapping underlying complex structures. In this paper, we analyze the loss of functional connections of dementia networks in comparison with the network of average healthy control (HC) subjects. We then perform the topological quantification of the minimum spanning tree (MST) networks using graph theory metrics to identify the brain functional networks of MCI, AD and VD in comparison with healthy control (HC) subjects. A common reactive band is identified and MST is formed for all the subjects. The MST topological quantifications are used to identify the dementia related disorders based on the data recorded from 10 HC subjects and 30 dementia subjects. Our results show that the proposed approach has the potential to identify the dementia stages and can enhance the diagnosis of dementia related disorders.",
keywords = "Dementia, Electroencephalogram (EEG), Functional Connectivity, Graph Theory, Minimum Spanning Tree (MST), Mutual Information (MI), Reactive Band",
author = "Adebisi, {Abdulyekeen T.} and Venkateswarlu Gonuguntla and Lee, {Ho Won} and Veluvolu, {Kalyana C.}",
note = "Publisher Copyright: {\textcopyright} 2020 IEEE.; 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020 ; Conference date: 16-12-2020 Through 19-12-2020",
year = "2020",
month = dec,
day = "16",
doi = "10.1109/BIBM49941.2020.9313223",
language = "English",
series = "Proceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "1761--1768",
editor = "Taesung Park and Young-Rae Cho and Hu, {Xiaohua Tony} and Illhoi Yoo and Woo, {Hyun Goo} and Jianxin Wang and Julio Facelli and Seungyoon Nam and Mingon Kang",
booktitle = "Proceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020",
address = "United States",
}