TY - JOUR
T1 - Inflammatory reaction in the herniated degenerative disc materials in miniature dachshunds
AU - Shimizu, Junichiro
AU - Mochida, Kyohei
AU - Kobayashi, Yoshiyasu
AU - Kitamura, Masahiko
AU - Tanaka, Hiroshi
AU - Kishimoto, Miori
AU - Lee, Ki Ja
AU - Iwasaki, Toshiroh
AU - Miyake, Yoh Ichi
AU - Nakayama, Masanari
AU - Yamada, Kazutaka
PY - 2010/1
Y1 - 2010/1
N2 - Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.
AB - Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.
KW - Canine
KW - Inflammatory cell
KW - Intervertebral disc herniation
KW - Phagocytosis
KW - Spontaneous regression
UR - http://www.scopus.com/inward/record.url?scp=76449121615&partnerID=8YFLogxK
U2 - 10.1292/jvms.09-0221
DO - 10.1292/jvms.09-0221
M3 - Comment/debate
C2 - 19915338
AN - SCOPUS:76449121615
SN - 0916-7250
VL - 72
SP - 81
EP - 84
JO - Journal of Veterinary Medical Science
JF - Journal of Veterinary Medical Science
IS - 1
ER -