Inflammatory reaction in the herniated degenerative disc materials in miniature dachshunds

Junichiro Shimizu; Kyohei Mochida; Yoshiyasu Kobayashi; Masahiko Kitamura; Hiroshi Tanaka; Miori Kishimoto; Ki Ja Lee; Toshiroh Iwasaki; Yoh Ichi Miyake; Masanari Nakayama; Kazutaka Yamada

doi:10.1292/jvms.09-0221

Inflammatory reaction in the herniated degenerative disc materials in miniature dachshunds

Junichiro Shimizu
, Kyohei Mochida
, Yoshiyasu Kobayashi
, Masahiko Kitamura
, Hiroshi Tanaka
, Miori Kishimoto
, Ki Ja Lee
, Toshiroh Iwasaki
, Yoh Ichi Miyake
, Masanari Nakayama
, Kazutaka Yamada

Department of Veterinary Medicine

Obihiro University of Agriculture and Veterinary Medicine
Nakayama Veterinary Hospital
Tokyo University of Agriculture and Technology

Research output: Contribution to journal › Comment/debate

8 Scopus citations

Abstract

Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.

Original language	English
Pages (from-to)	81-84
Number of pages	4
Journal	Journal of Veterinary Medical Science
Volume	72
Issue number	1
DOIs	https://doi.org/10.1292/jvms.09-0221
State	Published - Jan 2010

Keywords

Canine
Inflammatory cell
Intervertebral disc herniation
Phagocytosis
Spontaneous regression

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10.1292/jvms.09-0221

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title = "Inflammatory reaction in the herniated degenerative disc materials in miniature dachshunds",

abstract = "Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.",

keywords = "Canine, Inflammatory cell, Intervertebral disc herniation, Phagocytosis, Spontaneous regression",

author = "Junichiro Shimizu and Kyohei Mochida and Yoshiyasu Kobayashi and Masahiko Kitamura and Hiroshi Tanaka and Miori Kishimoto and Lee, \{Ki Ja\} and Toshiroh Iwasaki and Miyake, \{Yoh Ichi\} and Masanari Nakayama and Kazutaka Yamada",

year = "2010",

month = jan,

doi = "10.1292/jvms.09-0221",

language = "English",

volume = "72",

pages = "81--84",

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TY - JOUR

T1 - Inflammatory reaction in the herniated degenerative disc materials in miniature dachshunds

AU - Shimizu, Junichiro

AU - Mochida, Kyohei

AU - Kobayashi, Yoshiyasu

AU - Kitamura, Masahiko

AU - Tanaka, Hiroshi

AU - Kishimoto, Miori

AU - Lee, Ki Ja

AU - Iwasaki, Toshiroh

AU - Miyake, Yoh Ichi

AU - Nakayama, Masanari

AU - Yamada, Kazutaka

PY - 2010/1

Y1 - 2010/1

N2 - Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.

AB - Histological and immunohistochemical studies were conducted using herniated intervertebral disc materials obtained surgically from 39 miniature dachshunds. Infiltration of inflammatory cells, such as macrophages, neutrophils, T or B lymphocytes, and multinucleated giant cells, were identified in intervertebral disc materials in 23 cases. Furthermore, proliferations of connective tissue, including neovascularization, were also observed in 17 cases. These results suggest that spontaneous regression of herniated intervertebral disc material could occur in affected dogs.

KW - Canine

KW - Inflammatory cell

KW - Intervertebral disc herniation

KW - Phagocytosis

KW - Spontaneous regression

UR - https://www.scopus.com/pages/publications/76449121615

U2 - 10.1292/jvms.09-0221

DO - 10.1292/jvms.09-0221

M3 - Comment/debate

C2 - 19915338

AN - SCOPUS:76449121615

SN - 0916-7250

VL - 72

SP - 81

EP - 84

JO - Journal of Veterinary Medical Science

JF - Journal of Veterinary Medical Science

IS - 1

ER -

Inflammatory reaction in the herniated degenerative disc materials in miniature dachshunds

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Keywords

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