Influence of sonication treatment on supramolecular cellulose microfibril-based hydrogels induced by ionic interaction

Nanang Masruchin; Byung Dae Park; Valerio Causin

doi:10.1016/j.jiec.2015.03.034

Influence of sonication treatment on supramolecular cellulose microfibril-based hydrogels induced by ionic interaction

Nanang Masruchin, Byung Dae Park, Valerio Causin

School of Forest Sciences and Landscape

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

This study investigated effects of sonication treatment on characteristics and drug release behavior of hydrogels prepared by supramolecular cellulose microfibrils (CMFs) isolated by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation which made carboxylate negative charge available on the CMFs' surface. The hydrogels were fabricated by inducing ionic interactions between negatively charged CMFs and a positive metal ion (Al³⁺). The sonication time showed no influence on the carboxylate content of CMFs, but it greatly influenced characteristics and drug release behavior of the hydrogels. These results indicate that the sonication time has an impact on hydrogels' characteristics and drug release behavior.

Original language	English
Pages (from-to)	265-272
Number of pages	8
Journal	Journal of Industrial and Engineering Chemistry
Volume	29
DOIs	https://doi.org/10.1016/j.jiec.2015.03.034
State	Published - 25 Sep 2015

Keywords

Cellulose microfibrils
Drug release
Hydrogel
Ionic cross-linking
Sonication

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10.1016/j.jiec.2015.03.034

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title = "Influence of sonication treatment on supramolecular cellulose microfibril-based hydrogels induced by ionic interaction",

abstract = "This study investigated effects of sonication treatment on characteristics and drug release behavior of hydrogels prepared by supramolecular cellulose microfibrils (CMFs) isolated by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation which made carboxylate negative charge available on the CMFs' surface. The hydrogels were fabricated by inducing ionic interactions between negatively charged CMFs and a positive metal ion (Al3+). The sonication time showed no influence on the carboxylate content of CMFs, but it greatly influenced characteristics and drug release behavior of the hydrogels. These results indicate that the sonication time has an impact on hydrogels' characteristics and drug release behavior.",

keywords = "Cellulose microfibrils, Drug release, Hydrogel, Ionic cross-linking, Sonication",

author = "Nanang Masruchin and Park, {Byung Dae} and Valerio Causin",

note = "Publisher Copyright: {\textcopyright} 2015 The Korean Society of Industrial and Engineering Chemistry.",

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doi = "10.1016/j.jiec.2015.03.034",

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T1 - Influence of sonication treatment on supramolecular cellulose microfibril-based hydrogels induced by ionic interaction

AU - Masruchin, Nanang

AU - Park, Byung Dae

AU - Causin, Valerio

PY - 2015/9/25

Y1 - 2015/9/25

N2 - This study investigated effects of sonication treatment on characteristics and drug release behavior of hydrogels prepared by supramolecular cellulose microfibrils (CMFs) isolated by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation which made carboxylate negative charge available on the CMFs' surface. The hydrogels were fabricated by inducing ionic interactions between negatively charged CMFs and a positive metal ion (Al3+). The sonication time showed no influence on the carboxylate content of CMFs, but it greatly influenced characteristics and drug release behavior of the hydrogels. These results indicate that the sonication time has an impact on hydrogels' characteristics and drug release behavior.

AB - This study investigated effects of sonication treatment on characteristics and drug release behavior of hydrogels prepared by supramolecular cellulose microfibrils (CMFs) isolated by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation which made carboxylate negative charge available on the CMFs' surface. The hydrogels were fabricated by inducing ionic interactions between negatively charged CMFs and a positive metal ion (Al3+). The sonication time showed no influence on the carboxylate content of CMFs, but it greatly influenced characteristics and drug release behavior of the hydrogels. These results indicate that the sonication time has an impact on hydrogels' characteristics and drug release behavior.

KW - Cellulose microfibrils

KW - Drug release

KW - Hydrogel

KW - Ionic cross-linking

KW - Sonication

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SN - 1226-086X

VL - 29

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EP - 272

JO - Journal of Industrial and Engineering Chemistry

JF - Journal of Industrial and Engineering Chemistry

ER -

Influence of sonication treatment on supramolecular cellulose microfibril-based hydrogels induced by ionic interaction

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Keywords

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