Inhibition effect against elastase, collagenase, hyaluronidase and anti-oxidant activity of thinning green ball apple

Yu Jin Go, Ye Eun Kim, Hyun Nam Kim, Eun Ho Lee, Eun Bi Cho, Akhmadjon Sultanov, Soon Il Kwon, Young Je Cho

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

In this study, the anti-oxidative, health functional, and beauty food activities of water and ethanol extracts from newly bred Ruby S apple (Malus pumila Mill.). The results of measuring the 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity by treating the phenolic compound with thinning green ball apple at a concentration of 50-200 µg/mL showed that the water and ethanol extracts at a concentration of 200 µg/mL showed 94.69 and 92.24%, respectively. 2,2'-Azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activities showed 100.30 and 99.16%, respectively, in 200 µg/mL of water and ethanol extracts. The water and ethanol extracts of Green ball showed antioxidant protection factor of 1.76 PF 1.76, respectively. The water and ethanol extracts showed 101.46 and 99.64% anti-oxidative effect on thiobarbituric acid reactive substances at phenolic concentration of 200 µg/mL. The water and ethanol extracts showed 33.28 and 32.14% hyaluronidase inhibition, respectively, at phenolic concentration of 150 µg/mL. The water and ethanol extracts showed 47.33 and 40.92% elastase inhibition and 46.19 and 65.58% collagenase inhibition at phenolic concentration of 200 µg/mL, respectively. About these experiments, thinning Green ball apple was found to exhibit anti-oxidation activity as well as hyaluronidase, elastase and collagenase inhibitory activities. Therefore, thinning Green ball apple can be considered a potential sources for new functional materials.

Original languageEnglish
Pages (from-to)43-50
Number of pages8
JournalJournal of Applied Biological Chemistry
Volume63
Issue number1
DOIs
StatePublished - 2020

Keywords

  • Anti-oxidant
  • Collagenase
  • Elastase
  • Hyaluronidase
  • Thinning green ball apple

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