Inhibitors of osteoclast formation from rhizomes of Cibotium barometz

Xuan Cuong Nguyen, Van Minh Chau, Van Kiem Phan, Thanh Huong Hoang, Khac Ban Ninh, Xuan Nhiem Nguyen, Huu Tung Nguyen, Ji Won Jung, Hyun Ju Kim, Shin Yoon Kim, Ah Kim Jeong, Ho Kim Young

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

Eight compounds (1-8) were isolated from a methanol extract of Cibotium barometz rhizomes including two new furan derivatives, cibotiumbarosides A (1) and B (2), and a new glycoglycerolipid, cibotiglycerol (4). Their structures were elucidated by chemical and spectroscopic methods. Compounds 2-5 each showed inhibition of osteoclast formation with no affect on BMM cell viability.

Original languageEnglish
Pages (from-to)1673-1677
Number of pages5
JournalJournal of Natural Products
Volume72
Issue number9
DOIs
StatePublished - 25 Sep 2009

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