Integration of Forward-viewing and Side-viewing Ultrasound Transducers in an Intravascular Sonothrombolysis Catheter

Bohua Zhang, Huaiyu Wu, Jinwook Kim, Paul Dayton, Zhen Xu, Xiaoning Jiang

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Thrombosis has emerged as one of the primary factors in mortality rates across the world. Conventional thrombolysis treatments for the rapid dissolution or extraction of massive thrombus, including fibrinolytic therapy and surgical thrombectomy, are time-consuming and may induce risks such as bleeding and vessel wall damage. Here we report a novel intravascular sonothrombolysis device with both forward-viewing and side-viewing elements. The developed FSV transducer prototype has a resonance frequency at 520 kHz and peak negative pressure (PNP) at 4.9 MPa (forward-viewing) and 3.2 MPa (side-viewing) under the driving voltage of 80 V pp. The combination of forward and side-viewing (FSV) ultrasound waves is expected to extend the treatment region and improve thrombolysis efficiency compared to a forward or side-viewing alone sonication.

Original languageEnglish
Title of host publicationIUS 2022 - IEEE International Ultrasonics Symposium
PublisherIEEE Computer Society
ISBN (Electronic)9781665466578
DOIs
StatePublished - 2022
Event2022 IEEE International Ultrasonics Symposium, IUS 2022 - Venice, Italy
Duration: 10 Oct 202213 Oct 2022

Publication series

NameIEEE International Ultrasonics Symposium, IUS
Volume2022-October
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2022 IEEE International Ultrasonics Symposium, IUS 2022
Country/TerritoryItaly
CityVenice
Period10/10/2213/10/22

Keywords

  • microbubbles
  • sonothrombolysis
  • thrombolysis
  • thrombus
  • ultrasound transducers

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