Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01)

Kyubo Kim; Minsoo Chun; Hyeongmin Jin; Wonguen Jung; Kyung Hwan Shin; Seong Soo Shin; Yeon Joo Kim; Shin Hyung Park; Jin Hee Kim; Yong Ho Kim; Hyun Soo Shin; Haeyoung Kim; Su Ssan Kim; Jong Hoon Lee; Yong Bae Kim; Sun Young Lee; Jinhyun Choi; Do Hoon Oh; Ki Mun Kang; Jeanny Kwon; Mi Young Kim; Taeryool Koo; Hae Jin Park; Sung Ja Ahn

doi:10.21873/anticanres.15100

Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01)

Kyubo Kim, Minsoo Chun, Hyeongmin Jin, Wonguen Jung, Kyung Hwan Shin, Seong Soo Shin, Yeon Joo Kim, Shin Hyung Park, Jin Hee Kim, Yong Ho Kim, Hyun Soo Shin, Haeyoung Kim, Su Ssan Kim, Jong Hoon Lee, Yong Bae Kim, Sun Young Lee, Jinhyun Choi, Do Hoon Oh, Ki Mun Kang, Jeanny KwonMi Young Kim, Taeryool Koo, Hae Jin Park, Sung Ja Ahn

Department of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Background/Aim: To present the variations in the target delineation and the planning results of intensity-modulated radiation therapy (IMRT) for breast cancers. Patients and Methods: We requested the target volumes and organs at risk delineation for two cases of left breast cancers, and evaluated the IMRT plans including the supraclavicular and internal mammary node irradiation. Results: Twenty-one institutions participated in this study. Differences in the planning target volume among institutions reached up to three-times for breast-conserving surgery (BCS) case and five-times for mastectomy case. Mean heart doses ranged from 3.3 to 24.1 Gy for BCS case and from 5.0 to 26.5 Gy for mastectomy case. Ipsilateral lung volumes receiving more than 20 Gy ranged from 4.7 to 57.4% for BCS case and from 16.4 to 55.5% for mastectomy case. Conclusion: There were large variations in the target delineation and planning results of IMRT for breast cancers among institutions. Considering the increased use of breast IMRT, more standardized protocols are needed.

Original language	English
Pages (from-to)	3145-3152
Number of pages	8
Journal	Anticancer Research
Volume	41
Issue number	6
DOIs	https://doi.org/10.21873/anticanres.15100
State	Published - Jun 2021

Keywords

Breast cancer
Dose-volume constraint
Intensity-modulated radiation therapy
Target volume
Variation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.21873/anticanres.15100

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Kim, K., Chun, M., Jin, H., Jung, W., Shin, K. H., Shin, S. S., Kim, Y. J., Park, S. H., Kim, J. H., Kim, Y. H., Shin, H. S., Kim, H., Kim, S. S., Lee, J. H., Kim, Y. B., Lee, S. Y., Choi, J., Oh, D. H., Kang, K. M., ... Ahn, S. J. (2021). Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01). Anticancer Research, 41(6), 3145-3152. https://doi.org/10.21873/anticanres.15100

@article{ab583f679859447d9cf9baf80898385b,

title = "Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01)",

abstract = "Background/Aim: To present the variations in the target delineation and the planning results of intensity-modulated radiation therapy (IMRT) for breast cancers. Patients and Methods: We requested the target volumes and organs at risk delineation for two cases of left breast cancers, and evaluated the IMRT plans including the supraclavicular and internal mammary node irradiation. Results: Twenty-one institutions participated in this study. Differences in the planning target volume among institutions reached up to three-times for breast-conserving surgery (BCS) case and five-times for mastectomy case. Mean heart doses ranged from 3.3 to 24.1 Gy for BCS case and from 5.0 to 26.5 Gy for mastectomy case. Ipsilateral lung volumes receiving more than 20 Gy ranged from 4.7 to 57.4% for BCS case and from 16.4 to 55.5% for mastectomy case. Conclusion: There were large variations in the target delineation and planning results of IMRT for breast cancers among institutions. Considering the increased use of breast IMRT, more standardized protocols are needed.",

keywords = "Breast cancer, Dose-volume constraint, Intensity-modulated radiation therapy, Target volume, Variation",

author = "Kyubo Kim and Minsoo Chun and Hyeongmin Jin and Wonguen Jung and Shin, {Kyung Hwan} and Shin, {Seong Soo} and Kim, {Yeon Joo} and Park, {Shin Hyung} and Kim, {Jin Hee} and Kim, {Yong Ho} and Shin, {Hyun Soo} and Haeyoung Kim and Kim, {Su Ssan} and Lee, {Jong Hoon} and Kim, {Yong Bae} and Lee, {Sun Young} and Jinhyun Choi and Oh, {Do Hoon} and Kang, {Ki Mun} and Jeanny Kwon and Kim, {Mi Young} and Taeryool Koo and Park, {Hae Jin} and Ahn, {Sung Ja}",

year = "2021",

month = jun,

doi = "10.21873/anticanres.15100",

language = "English",

volume = "41",

pages = "3145--3152",

journal = "Anticancer Research",

issn = "0250-7005",

publisher = "International Institute of Anticancer Research",

number = "6",

}

Kim, K, Chun, M, Jin, H, Jung, W, Shin, KH, Shin, SS, Kim, YJ, Park, SH, Kim, JH, Kim, YH, Shin, HS, Kim, H, Kim, SS, Lee, JH, Kim, YB, Lee, SY, Choi, J, Oh, DH, Kang, KM, Kwon, J, Kim, MY, Koo, T, Park, HJ & Ahn, SJ 2021, 'Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01)', Anticancer Research, vol. 41, no. 6, pp. 3145-3152. https://doi.org/10.21873/anticanres.15100

TY - JOUR

T1 - Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01)

AU - Kim, Kyubo

AU - Chun, Minsoo

AU - Jin, Hyeongmin

AU - Jung, Wonguen

AU - Shin, Kyung Hwan

AU - Shin, Seong Soo

AU - Kim, Yeon Joo

AU - Park, Shin Hyung

AU - Kim, Jin Hee

AU - Kim, Yong Ho

AU - Shin, Hyun Soo

AU - Kim, Haeyoung

AU - Kim, Su Ssan

AU - Lee, Jong Hoon

AU - Kim, Yong Bae

AU - Lee, Sun Young

AU - Choi, Jinhyun

AU - Oh, Do Hoon

AU - Kang, Ki Mun

AU - Kwon, Jeanny

AU - Kim, Mi Young

AU - Koo, Taeryool

AU - Park, Hae Jin

AU - Ahn, Sung Ja

PY - 2021/6

Y1 - 2021/6

N2 - Background/Aim: To present the variations in the target delineation and the planning results of intensity-modulated radiation therapy (IMRT) for breast cancers. Patients and Methods: We requested the target volumes and organs at risk delineation for two cases of left breast cancers, and evaluated the IMRT plans including the supraclavicular and internal mammary node irradiation. Results: Twenty-one institutions participated in this study. Differences in the planning target volume among institutions reached up to three-times for breast-conserving surgery (BCS) case and five-times for mastectomy case. Mean heart doses ranged from 3.3 to 24.1 Gy for BCS case and from 5.0 to 26.5 Gy for mastectomy case. Ipsilateral lung volumes receiving more than 20 Gy ranged from 4.7 to 57.4% for BCS case and from 16.4 to 55.5% for mastectomy case. Conclusion: There were large variations in the target delineation and planning results of IMRT for breast cancers among institutions. Considering the increased use of breast IMRT, more standardized protocols are needed.

AB - Background/Aim: To present the variations in the target delineation and the planning results of intensity-modulated radiation therapy (IMRT) for breast cancers. Patients and Methods: We requested the target volumes and organs at risk delineation for two cases of left breast cancers, and evaluated the IMRT plans including the supraclavicular and internal mammary node irradiation. Results: Twenty-one institutions participated in this study. Differences in the planning target volume among institutions reached up to three-times for breast-conserving surgery (BCS) case and five-times for mastectomy case. Mean heart doses ranged from 3.3 to 24.1 Gy for BCS case and from 5.0 to 26.5 Gy for mastectomy case. Ipsilateral lung volumes receiving more than 20 Gy ranged from 4.7 to 57.4% for BCS case and from 16.4 to 55.5% for mastectomy case. Conclusion: There were large variations in the target delineation and planning results of IMRT for breast cancers among institutions. Considering the increased use of breast IMRT, more standardized protocols are needed.

KW - Breast cancer

KW - Dose-volume constraint

KW - Intensity-modulated radiation therapy

KW - Target volume

KW - Variation

UR - http://www.scopus.com/inward/record.url?scp=85107686487&partnerID=8YFLogxK

U2 - 10.21873/anticanres.15100

DO - 10.21873/anticanres.15100

M3 - Article

C2 - 34083309

AN - SCOPUS:85107686487

SN - 0250-7005

VL - 41

SP - 3145

EP - 3152

JO - Anticancer Research

JF - Anticancer Research

IS - 6

ER -

Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01)

Abstract

Keywords

UN SDGs

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