Interpersonal sensitivity and childhood trauma in patients with major depressive disorder, bipolar I, and II disorder

Sarah Soonji Kwon, Yoonjeong Jang, Ji Seon You, Chan Woo Lee, Hyeona Yu, Joohyun Yoon, Yun Seong Park, Hyun A. Ryoo, Daseul Lee, Nayoung Cho, Hong Kyu Ihm, Yeong Chan Lee, Hong Hee Won, Hyo Shin Kang, Tae Hyon Ha, Woojae Myung

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Childhood trauma and interpersonal sensitivity impact the development of mood disorders. In this study, we investigate the association between childhood trauma and interpersonal sensitivity in patients with mood disorders. A total 775 patients (major depressive disorder [MDD, n = 241], bipolar I disorder [BD I, n = 119], and bipolar II disorder [BD II, n = 415]) and 734 controls. For evaluation, we used the Childhood Trauma Questionnaire-Short Form (CTQ) and Interpersonal Sensitivity Measure (IPSM). We examined between-group differences for each subscale in the CTQ and IPSM. Patients with BD II had significantly higher IPSM total scores than patients with MDD, BD I, or controls. The CTQ total score was related to the IPSM total score in all participants and subgroups. Among the CTQ subscales, emotional abuse showed the highest correlation with the IPSM total score, while separation anxiety and fragile inner self showed higher positive correlations with CTQ than the other subscales of IPSM in all patient groups and the control group, respectively. The findings reveal that childhood trauma and interpersonal sensitivity are positively correlated among patients with MDD, BD I, and BD II, and that interpersonal sensitivity is higher in patients with BD II than those with BD I or MDD. Childhood trauma is associated with interpersonal sensitivity, and each trauma type has a different impact on mood disorders. We expect that this study will encourage future research on interpersonal sensitivity and childhood trauma in mood disorders to improve treatment approaches.

Original languageEnglish
Pages (from-to)537-547
Number of pages11
JournalEuropean Archives of Psychiatry and Clinical Neuroscience
Volume274
Issue number3
DOIs
StatePublished - Apr 2024

Keywords

  • Bipolar disorders
  • Childhood trauma
  • Interpersonal sensitivity
  • Major depressive disorder

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