Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07

Guehwan Jang; Seong Hee Kim; Yoo Jin Lee; Seungjoon Kim; Du Sik Lee; Kyoung Ki Lee; Changhee Lee

doi:10.4142/jvs.2018.19.4.577

Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07

Guehwan Jang, Seong Hee Kim, Yoo Jin Lee, Seungjoon Kim, Du Sik Lee, Kyoung Ki Lee, Changhee Lee

Department of Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.

Original language	English
Pages (from-to)	577-581
Number of pages	5
Journal	Journal of Veterinary Science
Volume	19
Issue number	4
DOIs	https://doi.org/10.4142/jvs.2018.19.4.577
State	Published - 2018

Keywords

Cell culture isolation
Genome analysis
Porcine deltacoronavirus
Virulence

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10.4142/jvs.2018.19.4.577

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abstract = "Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.",

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author = "Guehwan Jang and Kim, {Seong Hee} and Lee, {Yoo Jin} and Seungjoon Kim and Lee, {Du Sik} and Lee, {Kyoung Ki} and Changhee Lee",

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T1 - Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07

AU - Jang, Guehwan

AU - Kim, Seong Hee

AU - Lee, Yoo Jin

AU - Kim, Seungjoon

AU - Lee, Du Sik

AU - Lee, Kyoung Ki

AU - Lee, Changhee

PY - 2018

Y1 - 2018

N2 - Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.

AB - Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.

KW - Cell culture isolation

KW - Genome analysis

KW - Porcine deltacoronavirus

KW - Virulence

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JO - Journal of Veterinary Science

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ER -

Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07

Abstract

Keywords

UN SDGs

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