Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii

Eun Hyang Choi; Ji Young Choi; Jong Gu Lee; Joon Seok Oh; Dong Chun Kim; Hee Sang Lee; Jong Keun Son; Son Ae Ryang; Jeong Ah Kim; Seung Ho Lee

Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii

Eun Hyang Choi, Ji Young Choi, Jong Gu Lee, Joon Seok Oh, Dong Chun Kim, Hee Sang Lee, Jong Keun Son, Son Ae Ryang, Jeong Ah Kim, Seung Ho Lee

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione (1), (-)-asarinin (2), (-)-sesamin (3), eucarvone (4), methyleugenol (5), γ-asarone (6), pellitorine (7) and asarinol A (8) by analysis of spectral data. Among them, (-)-asarinin (2) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%.

Original language	English
Pages (from-to)	394-399
Number of pages	6
Journal	Korean Journal of Pharmacognosy
Volume	38
Issue number	4
State	Published - Dec 2007

Keywords

(-)-Asarinin
Asarum sieboldii
Melanogenesis inhibitor
Methyleugenol

Cite this

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title = "Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii",

abstract = "Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione (1), (-)-asarinin (2), (-)-sesamin (3), eucarvone (4), methyleugenol (5), γ-asarone (6), pellitorine (7) and asarinol A (8) by analysis of spectral data. Among them, (-)-asarinin (2) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%.",

keywords = "(-)-Asarinin, Asarum sieboldii, Melanogenesis inhibitor, Methyleugenol",

author = "Choi, {Eun Hyang} and Choi, {Ji Young} and Lee, {Jong Gu} and Oh, {Joon Seok} and Kim, {Dong Chun} and Lee, {Hee Sang} and Son, {Jong Keun} and Ryang, {Son Ae} and Kim, {Jeong Ah} and Lee, {Seung Ho}",

year = "2007",

month = dec,

language = "English",

volume = "38",

pages = "394--399",

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T1 - Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii

AU - Choi, Eun Hyang

AU - Choi, Ji Young

AU - Lee, Jong Gu

AU - Oh, Joon Seok

AU - Kim, Dong Chun

AU - Lee, Hee Sang

AU - Son, Jong Keun

AU - Ryang, Son Ae

AU - Kim, Jeong Ah

AU - Lee, Seung Ho

PY - 2007/12

Y1 - 2007/12

N2 - Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione (1), (-)-asarinin (2), (-)-sesamin (3), eucarvone (4), methyleugenol (5), γ-asarone (6), pellitorine (7) and asarinol A (8) by analysis of spectral data. Among them, (-)-asarinin (2) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%.

AB - Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione (1), (-)-asarinin (2), (-)-sesamin (3), eucarvone (4), methyleugenol (5), γ-asarone (6), pellitorine (7) and asarinol A (8) by analysis of spectral data. Among them, (-)-asarinin (2) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%.

KW - (-)-Asarinin

KW - Asarum sieboldii

KW - Melanogenesis inhibitor

KW - Methyleugenol

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M3 - Article

AN - SCOPUS:76649126239

SN - 0253-3073

VL - 38

SP - 394

EP - 399

JO - Korean Journal of Pharmacognosy

JF - Korean Journal of Pharmacognosy

IS - 4

ER -

Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii

Abstract

Keywords

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