Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii

Eun Hyang Choi; Ji Young Choi; Jong Gu Lee; Joon Seok Oh; Dong Chun Kim; Hee Sang Lee; Jong Keun Son; Son Ae Ryang; Jeong Ah Kim; Seung Ho Lee

Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii

Eun Hyang Choi
, Ji Young Choi
, Jong Gu Lee
, Joon Seok Oh
, Dong Chun Kim
, Hee Sang Lee
, Jong Keun Son
, Son Ae Ryang
, Jeong Ah Kim
, Seung Ho Lee

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione (1), (-)-asarinin (2), (-)-sesamin (3), eucarvone (4), methyleugenol (5), γ-asarone (6), pellitorine (7) and asarinol A (8) by analysis of spectral data. Among them, (-)-asarinin (2) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%.

Original language	English
Pages (from-to)	394-399
Number of pages	6
Journal	Korean Journal of Pharmacognosy
Volume	38
Issue number	4
State	Published - Dec 2007

Keywords

(-)-Asarinin
Asarum sieboldii
Melanogenesis inhibitor
Methyleugenol

Cite this

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title = "Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii",

abstract = "Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione (1), (-)-asarinin (2), (-)-sesamin (3), eucarvone (4), methyleugenol (5), γ-asarone (6), pellitorine (7) and asarinol A (8) by analysis of spectral data. Among them, (-)-asarinin (2) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66\%.",

keywords = "(-)-Asarinin, Asarum sieboldii, Melanogenesis inhibitor, Methyleugenol",

author = "Choi, \{Eun Hyang\} and Choi, \{Ji Young\} and Lee, \{Jong Gu\} and Oh, \{Joon Seok\} and Kim, \{Dong Chun\} and Lee, \{Hee Sang\} and Son, \{Jong Keun\} and Ryang, \{Son Ae\} and Kim, \{Jeong Ah\} and Lee, \{Seung Ho\}",

year = "2007",

month = dec,

language = "English",

volume = "38",

pages = "394--399",

journal = "Korean Journal of Pharmacognosy",

issn = "0253-3073",

publisher = "Korean Society of Pharmacognosy",

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}

TY - JOUR

T1 - Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii

AU - Choi, Eun Hyang

AU - Choi, Ji Young

AU - Lee, Jong Gu

AU - Oh, Joon Seok

AU - Kim, Dong Chun

AU - Lee, Hee Sang

AU - Son, Jong Keun

AU - Ryang, Son Ae

AU - Kim, Jeong Ah

AU - Lee, Seung Ho

PY - 2007/12

Y1 - 2007/12

N2 - Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione (1), (-)-asarinin (2), (-)-sesamin (3), eucarvone (4), methyleugenol (5), γ-asarone (6), pellitorine (7) and asarinol A (8) by analysis of spectral data. Among them, (-)-asarinin (2) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%.

AB - Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione (1), (-)-asarinin (2), (-)-sesamin (3), eucarvone (4), methyleugenol (5), γ-asarone (6), pellitorine (7) and asarinol A (8) by analysis of spectral data. Among them, (-)-asarinin (2) showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%.

KW - (-)-Asarinin

KW - Asarum sieboldii

KW - Melanogenesis inhibitor

KW - Methyleugenol

UR - https://www.scopus.com/pages/publications/76649126239

M3 - Article

AN - SCOPUS:76649126239

SN - 0253-3073

VL - 38

SP - 394

EP - 399

JO - Korean Journal of Pharmacognosy

JF - Korean Journal of Pharmacognosy

IS - 4

ER -

Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii

Abstract

Keywords

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