Isolation of virus-cell fusion inhibitory components from the stem bark of Styrax japonica S. et Z

Dung Gun Lee; Qinglong Jin; Hong Guang Jin; Ji Eun Shin; Eun Jin Choi; Eun Rhan Woo

doi:10.1007/s12272-010-0608-4

Isolation of virus-cell fusion inhibitory components from the stem bark of Styrax japonica S. et Z

Dung Gun Lee, Qinglong Jin, Hong Guang Jin, Ji Eun Shin, Eun Jin Choi, Eun Rhan Woo

Chosun University

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Five compounds, styraxjaponoside A (1), matairesinoside (2), egonol glucoside (3), dihydrodehydrodiconiferyl alcohol 9′-O-glucoside (4), and styraxjaponoside B (5) were isolated from the stem bark of Styrax japonica. Among them, compounds 1 and 5 showed significantly high virus-cell fusion inhibitory activity. In addition, compound 5 exhibited almost equivalent virus-cell fusion inhibitory activity to that of dextran sulfate, which is used as a positive control.

Original language	English
Pages (from-to)	863-866
Number of pages	4
Journal	Archives of Pharmacal Research
Volume	33
Issue number	6
DOIs	https://doi.org/10.1007/s12272-010-0608-4
State	Published - Jun 2010

Keywords

Anti-HIV
Fusion index
Lignan glycoside
Styrax japonica S. et Z.
Virus-cell fusion
gp120/41

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s12272-010-0608-4

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title = "Isolation of virus-cell fusion inhibitory components from the stem bark of Styrax japonica S. et Z",

abstract = "Five compounds, styraxjaponoside A (1), matairesinoside (2), egonol glucoside (3), dihydrodehydrodiconiferyl alcohol 9′-O-glucoside (4), and styraxjaponoside B (5) were isolated from the stem bark of Styrax japonica. Among them, compounds 1 and 5 showed significantly high virus-cell fusion inhibitory activity. In addition, compound 5 exhibited almost equivalent virus-cell fusion inhibitory activity to that of dextran sulfate, which is used as a positive control.",

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author = "Lee, {Dung Gun} and Qinglong Jin and Jin, {Hong Guang} and Shin, {Ji Eun} and Choi, {Eun Jin} and Woo, {Eun Rhan}",

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AU - Lee, Dung Gun

AU - Jin, Qinglong

AU - Jin, Hong Guang

AU - Shin, Ji Eun

AU - Choi, Eun Jin

AU - Woo, Eun Rhan

PY - 2010/6

Y1 - 2010/6

N2 - Five compounds, styraxjaponoside A (1), matairesinoside (2), egonol glucoside (3), dihydrodehydrodiconiferyl alcohol 9′-O-glucoside (4), and styraxjaponoside B (5) were isolated from the stem bark of Styrax japonica. Among them, compounds 1 and 5 showed significantly high virus-cell fusion inhibitory activity. In addition, compound 5 exhibited almost equivalent virus-cell fusion inhibitory activity to that of dextran sulfate, which is used as a positive control.

AB - Five compounds, styraxjaponoside A (1), matairesinoside (2), egonol glucoside (3), dihydrodehydrodiconiferyl alcohol 9′-O-glucoside (4), and styraxjaponoside B (5) were isolated from the stem bark of Styrax japonica. Among them, compounds 1 and 5 showed significantly high virus-cell fusion inhibitory activity. In addition, compound 5 exhibited almost equivalent virus-cell fusion inhibitory activity to that of dextran sulfate, which is used as a positive control.

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KW - Fusion index

KW - Lignan glycoside

KW - Styrax japonica S. et Z.

KW - Virus-cell fusion

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Isolation of virus-cell fusion inhibitory components from the stem bark of Styrax japonica S. et Z

Abstract

Keywords

UN SDGs

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