Ketones as a new synthon for quinoxaline synthesis

Chan Sik Cho, Wen Xiu Ren, Sang Chul Shim

Research output: Contribution to journalArticlepeer-review

70 Scopus citations

Abstract

o-Phenylenediamines react with an array of ketones in PEG-400 at 60 °C under an atmosphere of air in the presence of KOH to afford the corresponding quinoxalines in good yields.

Original languageEnglish
Pages (from-to)4665-4667
Number of pages3
JournalTetrahedron Letters
Volume48
Issue number27
DOIs
StatePublished - 2 Jul 2007

Keywords

  • Cyclization
  • Ketones
  • o-Phenylenediamines
  • Poly(ethylene glycol)
  • Quinoxalines

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