Laxative effect of peanut sprout extract

Ji Yeon Seo, Seong Soon Kim, Hyo Jung Kim, Kwang Hyeon Liu, Hak Yong Lee, Jong Sang Kim

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Certain phenolic compounds are known to exhibit laxative properties. Seed sprouts, such as those of peanut, are known to promote de novo biosynthesis of phenolic compounds. This study was conducted to examine the potential laxative properties of 80% (v/v) ethanolic extract of peanut sprout (PSE), which contains a high concentration of phenolic compounds such as resveratrol. For this, SD rats were orally administered PSE while a control group was incubated with saline. Laxative effects were examined in both groups of rats. Constipation induced by loperamide in SD rats was improved by administration of PSE. Constipated rats showed increased intestinal movement of BaSO4 upon administration of PSE compared to the control, and the groups administered 100 or 1,000 mg PSE/kg bw were not significantly different in transit time of the indicator. However, colon length was not statistically different among the experimental groups, although it was longer in the group incubated with 1 g PSE/kg bw compared to other groups. Further, there was no significant difference in stool number among the experimental groups. Taken together, these findings show that PSE has a laxative effect in a rat model of loperamide-induced constipation.

Original languageEnglish
Pages (from-to)262-266
Number of pages5
JournalNutrition Research and Practice
Volume7
Issue number4
DOIs
StatePublished - Aug 2013

Keywords

  • Constipation
  • Laxative effect
  • Peanut sprout

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