Leptin polymorphisms associated with carcass traits of meat in Korean cattle

Hyun Sub Cheong; Du Hak Yoon; Lyoung Hyo Kim; Byung Lae Park; Eui Ryong Chung; Han Ju Lee; Il Cheong Cheong; Sung Jong Oh; Hyoung Doo Shin

doi:10.5713/ajas.2006.1529

Leptin polymorphisms associated with carcass traits of meat in Korean cattle

Hyun Sub Cheong, Du Hak Yoon, Lyoung Hyo Kim, Byung Lae Park, Eui Ryong Chung, Han Ju Lee, Il Cheong Cheong, Sung Jong Oh, Hyoung Doo Shin

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Leptin has been investigated as a candidate gene for fat characteristics in beef cattle. Previously, we have reported 57 sequence variants discovered in Korean cattle (Bos Taurus coreanae). In this study, we examined the association between polymorphisms of leptin and carcass traits (cold carcass weight (CWT) and marbling score (Marb)) in Korean cattle. Among 57 polymorphisms, 11 common polymorphic sites were genotyped in our beef cattle (n = 437). Statistical analysis revealed that one single nucleotide polymorphism in coding exon (c.+411T>C (Al37A)) showed a significant association with the yield trait, CWT. The C-b<-aring genotypes (CC or CT) of c.+411T>C (A137A) showed the higher CWT (p = 0.006). c.+150C>G (S50S) also showed a significant association with the quality trait, Marb (p = 0.01). Our findings suggest that polymorphisms in leptin might be one of the important genetic factors that influence carcass yield and quality in beef cattle, especially in CWT and Marb.

Original language	English
Pages (from-to)	1529-1535
Number of pages	7
Journal	Asian-Australasian Journal of Animal Sciences
Volume	19
Issue number	11
DOIs	https://doi.org/10.5713/ajas.2006.1529
State	Published - Nov 2006

Keywords

Cold Carcass Weight
Leptin
Marbling Score
Polymorphism

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10.5713/ajas.2006.1529

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title = "Leptin polymorphisms associated with carcass traits of meat in Korean cattle",

abstract = "Leptin has been investigated as a candidate gene for fat characteristics in beef cattle. Previously, we have reported 57 sequence variants discovered in Korean cattle (Bos Taurus coreanae). In this study, we examined the association between polymorphisms of leptin and carcass traits (cold carcass weight (CWT) and marbling score (Marb)) in Korean cattle. Among 57 polymorphisms, 11 common polymorphic sites were genotyped in our beef cattle (n = 437). Statistical analysis revealed that one single nucleotide polymorphism in coding exon (c.+411T>C (Al37A)) showed a significant association with the yield trait, CWT. The C-b<-aring genotypes (CC or CT) of c.+411T>C (A137A) showed the higher CWT (p = 0.006). c.+150C>G (S50S) also showed a significant association with the quality trait, Marb (p = 0.01). Our findings suggest that polymorphisms in leptin might be one of the important genetic factors that influence carcass yield and quality in beef cattle, especially in CWT and Marb.",

keywords = "Cold Carcass Weight, Leptin, Marbling Score, Polymorphism",

author = "Cheong, {Hyun Sub} and Yoon, {Du Hak} and Kim, {Lyoung Hyo} and Park, {Byung Lae} and Chung, {Eui Ryong} and Lee, {Han Ju} and Cheong, {Il Cheong} and Oh, {Sung Jong} and Shin, {Hyoung Doo}",

year = "2006",

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doi = "10.5713/ajas.2006.1529",

language = "English",

volume = "19",

pages = "1529--1535",

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AU - Cheong, Hyun Sub

AU - Yoon, Du Hak

AU - Kim, Lyoung Hyo

AU - Park, Byung Lae

AU - Chung, Eui Ryong

AU - Lee, Han Ju

AU - Cheong, Il Cheong

AU - Oh, Sung Jong

AU - Shin, Hyoung Doo

PY - 2006/11

Y1 - 2006/11

N2 - Leptin has been investigated as a candidate gene for fat characteristics in beef cattle. Previously, we have reported 57 sequence variants discovered in Korean cattle (Bos Taurus coreanae). In this study, we examined the association between polymorphisms of leptin and carcass traits (cold carcass weight (CWT) and marbling score (Marb)) in Korean cattle. Among 57 polymorphisms, 11 common polymorphic sites were genotyped in our beef cattle (n = 437). Statistical analysis revealed that one single nucleotide polymorphism in coding exon (c.+411T>C (Al37A)) showed a significant association with the yield trait, CWT. The C-b<-aring genotypes (CC or CT) of c.+411T>C (A137A) showed the higher CWT (p = 0.006). c.+150C>G (S50S) also showed a significant association with the quality trait, Marb (p = 0.01). Our findings suggest that polymorphisms in leptin might be one of the important genetic factors that influence carcass yield and quality in beef cattle, especially in CWT and Marb.

AB - Leptin has been investigated as a candidate gene for fat characteristics in beef cattle. Previously, we have reported 57 sequence variants discovered in Korean cattle (Bos Taurus coreanae). In this study, we examined the association between polymorphisms of leptin and carcass traits (cold carcass weight (CWT) and marbling score (Marb)) in Korean cattle. Among 57 polymorphisms, 11 common polymorphic sites were genotyped in our beef cattle (n = 437). Statistical analysis revealed that one single nucleotide polymorphism in coding exon (c.+411T>C (Al37A)) showed a significant association with the yield trait, CWT. The C-b<-aring genotypes (CC or CT) of c.+411T>C (A137A) showed the higher CWT (p = 0.006). c.+150C>G (S50S) also showed a significant association with the quality trait, Marb (p = 0.01). Our findings suggest that polymorphisms in leptin might be one of the important genetic factors that influence carcass yield and quality in beef cattle, especially in CWT and Marb.

KW - Cold Carcass Weight

KW - Leptin

KW - Marbling Score

KW - Polymorphism

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JF - Asian-Australasian Journal of Animal Sciences

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Leptin polymorphisms associated with carcass traits of meat in Korean cattle

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Keywords

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