Liquid-crystal-based biosensor for detecting Ca                         2+                          in human saliva

Dong Hyun Yeo; Soo Young Park

doi:10.1016/j.jiec.2019.03.001

Liquid-crystal-based biosensor for detecting Ca ²⁺ in human saliva

Dong Hyun Yeo, Soo Young Park

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A transmission electron microscopy Cu grid cell filled with 4-cyano-4′-pentylbiphenyl (5CB) was utilised for detecting Ca ²⁺ ion after functionalising the water/5CB interface with poly(acrylic acid)-b-poly(4-cyanobiphenyl-4′-oxyundecylacrylate) (PAA-b-LCP), wherein the LCP block was anchored to 5CB and the PAA block complexed with metal ions in water. The NaCl-treated cell exhibited homeotropic-to-planar orientational change when Ca ²⁺ ions were injected into the aqueous phase owing to the replacement of the Na ⁺ ions in the PAA chains with Ca ²⁺ ions. The performance of the cell in detecting Ca ²⁺ ions in human saliva was successfully verified to demonstrate the non-invasive detection.

Original language	English
Pages (from-to)	193-198
Number of pages	6
Journal	Journal of Industrial and Engineering Chemistry
Volume	74
DOIs	https://doi.org/10.1016/j.jiec.2019.03.001
State	Published - 25 Jun 2019

Keywords

Biosensor
Calcium ion
Liquid crystal
Non-invasive
Saliva
Transmission electron microscopy copper grid

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10.1016/j.jiec.2019.03.001

Cite this

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title = " Liquid-crystal-based biosensor for detecting Ca 2+ in human saliva ",

abstract = " A transmission electron microscopy Cu grid cell filled with 4-cyano-4′-pentylbiphenyl (5CB) was utilised for detecting Ca 2+ ion after functionalising the water/5CB interface with poly(acrylic acid)-b-poly(4-cyanobiphenyl-4′-oxyundecylacrylate) (PAA-b-LCP), wherein the LCP block was anchored to 5CB and the PAA block complexed with metal ions in water. The NaCl-treated cell exhibited homeotropic-to-planar orientational change when Ca 2+ ions were injected into the aqueous phase owing to the replacement of the Na + ions in the PAA chains with Ca 2+ ions. The performance of the cell in detecting Ca 2+ ions in human saliva was successfully verified to demonstrate the non-invasive detection.",

keywords = "Biosensor, Calcium ion, Liquid crystal, Non-invasive, Saliva, Transmission electron microscopy copper grid",

author = "Yeo, {Dong Hyun} and Park, {Soo Young}",

note = "Publisher Copyright: {\textcopyright} 2019 The Korean Society of Industrial and Engineering Chemistry",

year = "2019",

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doi = "10.1016/j.jiec.2019.03.001",

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journal = "Journal of Industrial and Engineering Chemistry",

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T1 - Liquid-crystal-based biosensor for detecting Ca 2+ in human saliva

AU - Yeo, Dong Hyun

AU - Park, Soo Young

PY - 2019/6/25

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N2 - A transmission electron microscopy Cu grid cell filled with 4-cyano-4′-pentylbiphenyl (5CB) was utilised for detecting Ca 2+ ion after functionalising the water/5CB interface with poly(acrylic acid)-b-poly(4-cyanobiphenyl-4′-oxyundecylacrylate) (PAA-b-LCP), wherein the LCP block was anchored to 5CB and the PAA block complexed with metal ions in water. The NaCl-treated cell exhibited homeotropic-to-planar orientational change when Ca 2+ ions were injected into the aqueous phase owing to the replacement of the Na + ions in the PAA chains with Ca 2+ ions. The performance of the cell in detecting Ca 2+ ions in human saliva was successfully verified to demonstrate the non-invasive detection.

AB - A transmission electron microscopy Cu grid cell filled with 4-cyano-4′-pentylbiphenyl (5CB) was utilised for detecting Ca 2+ ion after functionalising the water/5CB interface with poly(acrylic acid)-b-poly(4-cyanobiphenyl-4′-oxyundecylacrylate) (PAA-b-LCP), wherein the LCP block was anchored to 5CB and the PAA block complexed with metal ions in water. The NaCl-treated cell exhibited homeotropic-to-planar orientational change when Ca 2+ ions were injected into the aqueous phase owing to the replacement of the Na + ions in the PAA chains with Ca 2+ ions. The performance of the cell in detecting Ca 2+ ions in human saliva was successfully verified to demonstrate the non-invasive detection.

KW - Biosensor

KW - Calcium ion

KW - Liquid crystal

KW - Non-invasive

KW - Saliva

KW - Transmission electron microscopy copper grid

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DO - 10.1016/j.jiec.2019.03.001

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SN - 1226-086X

VL - 74

SP - 193

EP - 198

JO - Journal of Industrial and Engineering Chemistry

JF - Journal of Industrial and Engineering Chemistry

ER -

Liquid-crystal-based biosensor for detecting Ca ²⁺ in human saliva

Abstract

Keywords

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