Longitudinal water proton relaxivities of ultrasmall 3d and 4f transition metal oxide nanoparticles

Eun Sook Choi; Ja Young Park; Krishna Kattel; Wenlong Xu; Gang Ho Lee; Myung Ju Baek; Joo Hyun Kim; Yongmin Chang; Tae Jeong Kim

doi:10.3938/jkps.56.1532

Longitudinal water proton relaxivities of ultrasmall 3d and 4f transition metal oxide nanoparticles

Eun Sook Choi, Ja Young Park, Krishna Kattel, Wenlong Xu, Gang Ho Lee, Myung Ju Baek, Joo Hyun Kim, Yongmin Chang, Tae Jeong Kim

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

We report the longitudinal water proton relaxivities (r₁) of several 3d and 3f transition metal oxide nanoparticles. These include ultrasmall iron oxide, manganese oxide, europium oxide, gadolinium oxide, and dysprosium oxide nanoparticles. The nanoparticles ranged from 1.0 to 3.0 nm in diameter. Ultrasmall metal oxide nanoparticles with metal ions of high and pure S-state electron magnetic moments showed high r₁ relaxivities. The measured relaxivities indicate that ultrasmall gadolinium oxide nanoparticles with a high r₁ relaxivity of 12.6 mM^-1s^-1 may be suitable for use as a sensitive T₁ MRI contrast agent.

Original language	English
Pages (from-to)	1532-1536
Number of pages	5
Journal	Journal of the Korean Physical Society
Volume	56
Issue number	5
DOIs	https://doi.org/10.3938/jkps.56.1532
State	Published - 14 May 2010

Keywords

Longitudinal relaxivity
Metal oxide nanoparticle
Mri contrast agent
Ultrasmall

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title = "Longitudinal water proton relaxivities of ultrasmall 3d and 4f transition metal oxide nanoparticles",

abstract = "We report the longitudinal water proton relaxivities (r1) of several 3d and 3f transition metal oxide nanoparticles. These include ultrasmall iron oxide, manganese oxide, europium oxide, gadolinium oxide, and dysprosium oxide nanoparticles. The nanoparticles ranged from 1.0 to 3.0 nm in diameter. Ultrasmall metal oxide nanoparticles with metal ions of high and pure S-state electron magnetic moments showed high r1 relaxivities. The measured relaxivities indicate that ultrasmall gadolinium oxide nanoparticles with a high r1 relaxivity of 12.6 mM-1s-1 may be suitable for use as a sensitive T1 MRI contrast agent.",

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TY - JOUR

T1 - Longitudinal water proton relaxivities of ultrasmall 3d and 4f transition metal oxide nanoparticles

AU - Choi, Eun Sook

AU - Park, Ja Young

AU - Kattel, Krishna

AU - Xu, Wenlong

AU - Lee, Gang Ho

AU - Baek, Myung Ju

AU - Kim, Joo Hyun

AU - Chang, Yongmin

AU - Kim, Tae Jeong

PY - 2010/5/14

Y1 - 2010/5/14

N2 - We report the longitudinal water proton relaxivities (r1) of several 3d and 3f transition metal oxide nanoparticles. These include ultrasmall iron oxide, manganese oxide, europium oxide, gadolinium oxide, and dysprosium oxide nanoparticles. The nanoparticles ranged from 1.0 to 3.0 nm in diameter. Ultrasmall metal oxide nanoparticles with metal ions of high and pure S-state electron magnetic moments showed high r1 relaxivities. The measured relaxivities indicate that ultrasmall gadolinium oxide nanoparticles with a high r1 relaxivity of 12.6 mM-1s-1 may be suitable for use as a sensitive T1 MRI contrast agent.

AB - We report the longitudinal water proton relaxivities (r1) of several 3d and 3f transition metal oxide nanoparticles. These include ultrasmall iron oxide, manganese oxide, europium oxide, gadolinium oxide, and dysprosium oxide nanoparticles. The nanoparticles ranged from 1.0 to 3.0 nm in diameter. Ultrasmall metal oxide nanoparticles with metal ions of high and pure S-state electron magnetic moments showed high r1 relaxivities. The measured relaxivities indicate that ultrasmall gadolinium oxide nanoparticles with a high r1 relaxivity of 12.6 mM-1s-1 may be suitable for use as a sensitive T1 MRI contrast agent.

KW - Longitudinal relaxivity

KW - Metal oxide nanoparticle

KW - Mri contrast agent

KW - Ultrasmall

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DO - 10.3938/jkps.56.1532

M3 - Article

AN - SCOPUS:77954839102

SN - 0374-4884

VL - 56

SP - 1532

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JO - Journal of the Korean Physical Society

JF - Journal of the Korean Physical Society

IS - 5

ER -

Longitudinal water proton relaxivities of ultrasmall 3d and 4f transition metal oxide nanoparticles

Abstract

Keywords

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