Measuring primate RNFL thickness with OCT

Joshua Fox; Jason Marsack; Jeehyun Kim; Sharon Thomsen; H. Grady Rylander; Thomas E. Milner

doi:10.1109/2944.983291

Measuring primate RNFL thickness with OCT

Joshua Fox, Jason Marsack, Jeehyun Kim, Sharon Thomsen, H. Grady Rylander, Thomas E. Milner

School of Electronics Engineering

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We report results of a study using optical coherence tomography (OCT) to create area maps of the retinal nerve fiber layer (RNFL) thickness. Low-resolution B scans (two-dimensional images) of the in vivo rhesus monkey retina have been recorded in the optic disk, peripapillary area, and macula. Three-dimensional (3-D) renderings of these areas have been created from OCT images and compared to corresponding data from histology. Results of our study indicate: 1) OCT may be utilized to measure the retinal nerve fiber layer thickness in vivo and 2) 3-D surface maps accurately depict the anatomy of the RNFL.

Original language	English
Pages (from-to)	899-905
Number of pages	7
Journal	IEEE Journal of Selected Topics in Quantum Electronics
Volume	7
Issue number	6
DOIs	https://doi.org/10.1109/2944.983291
State	Published - Nov 2001

Keywords

Area map
Glaucoma
OCT
Optic nerve
Retinal histology
Retinal nerve fiber layer (RNFL)

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10.1109/2944.983291

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title = "Measuring primate RNFL thickness with OCT",

abstract = "We report results of a study using optical coherence tomography (OCT) to create area maps of the retinal nerve fiber layer (RNFL) thickness. Low-resolution B scans (two-dimensional images) of the in vivo rhesus monkey retina have been recorded in the optic disk, peripapillary area, and macula. Three-dimensional (3-D) renderings of these areas have been created from OCT images and compared to corresponding data from histology. Results of our study indicate: 1) OCT may be utilized to measure the retinal nerve fiber layer thickness in vivo and 2) 3-D surface maps accurately depict the anatomy of the RNFL.",

keywords = "Area map, Glaucoma, OCT, Optic nerve, Retinal histology, Retinal nerve fiber layer (RNFL)",

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AU - Fox, Joshua

AU - Marsack, Jason

AU - Kim, Jeehyun

AU - Thomsen, Sharon

AU - Rylander, H. Grady

AU - Milner, Thomas E.

PY - 2001/11

Y1 - 2001/11

N2 - We report results of a study using optical coherence tomography (OCT) to create area maps of the retinal nerve fiber layer (RNFL) thickness. Low-resolution B scans (two-dimensional images) of the in vivo rhesus monkey retina have been recorded in the optic disk, peripapillary area, and macula. Three-dimensional (3-D) renderings of these areas have been created from OCT images and compared to corresponding data from histology. Results of our study indicate: 1) OCT may be utilized to measure the retinal nerve fiber layer thickness in vivo and 2) 3-D surface maps accurately depict the anatomy of the RNFL.

AB - We report results of a study using optical coherence tomography (OCT) to create area maps of the retinal nerve fiber layer (RNFL) thickness. Low-resolution B scans (two-dimensional images) of the in vivo rhesus monkey retina have been recorded in the optic disk, peripapillary area, and macula. Three-dimensional (3-D) renderings of these areas have been created from OCT images and compared to corresponding data from histology. Results of our study indicate: 1) OCT may be utilized to measure the retinal nerve fiber layer thickness in vivo and 2) 3-D surface maps accurately depict the anatomy of the RNFL.

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KW - Glaucoma

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KW - Optic nerve

KW - Retinal histology

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Measuring primate RNFL thickness with OCT

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