Microwave-assisted copper powder-catalyzed coupling and cyclization of β-bromo-α,β-unsaturated amides with amidine hydrochlorides leading to pyrimidinones

Yang Jiao, Chan Sik Cho

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

β-Bromo-α,β-unsaturated amides are coupled and cyclized with amidine hydrochlorides using microwave irradiation in the presence of a catalytic amount of copper powder and a base to give the corresponding pyrimidinones in good yields.

Original languageEnglish
Pages (from-to)372-375
Number of pages4
JournalApplied Organometallic Chemistry
Volume29
Issue number6
DOIs
StatePublished - 1 Jun 2015

Keywords

  • copper powder
  • cyclization
  • heterocycles
  • heterogeneous catalysis
  • microwaves

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