Abstract
β-Bromo α,β-unsaturated carboxylic acids were coupled and cyclized with amidine hydrochlorides by microwave irradiation in the presence of catalytic amounts of copper powder and a base to give the corresponding pyrimidinones in high yields.
| Original language | English |
|---|---|
| Article number | ST-2013-U0835-L |
| Pages (from-to) | 2705-2708 |
| Number of pages | 4 |
| Journal | Synlett |
| Volume | 24 |
| Issue number | 20 |
| DOIs | |
| State | Published - 17 Dec 2013 |
Keywords
- copper
- coupling
- cyclization
- heterocycles
- heterogeneous catalysis