Microwave-assisted green construction of imidazole-fused hybrid scaffolds using 2-aminobenzimidazoles as building blocks

Jung Pyo Kwak; Pham Duy Quang Dao; Nam Sik Yoon; Chan Sik Cho

doi:10.1039/d1ra04396j

Microwave-assisted green construction of imidazole-fused hybrid scaffolds using 2-aminobenzimidazoles as building blocks

Jung Pyo Kwak, Pham Duy Quang Dao, Nam Sik Yoon, Chan Sik Cho

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A class of trinuclear imidazole-fused hybrid scaffolds was constructed by the reaction of 2-(2-bromoaryl)- and 2-(2-bromovinyl)imidazoles with 2-aminobenzimidazoles as building blocks in the presence of a base under microwave irradiation. A nucleophilic aromatic substitution followed by cyclization is proposed as a reaction pathway of this green process.

Original language	English
Pages (from-to)	21367-21374
Number of pages	8
Journal	RSC Advances
Volume	11
Issue number	35
DOIs	https://doi.org/10.1039/d1ra04396j
State	Published - 17 Jun 2021

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10.1039/d1ra04396j

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title = "Microwave-assisted green construction of imidazole-fused hybrid scaffolds using 2-aminobenzimidazoles as building blocks",

abstract = "A class of trinuclear imidazole-fused hybrid scaffolds was constructed by the reaction of 2-(2-bromoaryl)- and 2-(2-bromovinyl)imidazoles with 2-aminobenzimidazoles as building blocks in the presence of a base under microwave irradiation. A nucleophilic aromatic substitution followed by cyclization is proposed as a reaction pathway of this green process.",

author = "Kwak, \{Jung Pyo\} and \{Quang Dao\}, \{Pham Duy\} and Yoon, \{Nam Sik\} and Cho, \{Chan Sik\}",

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AU - Kwak, Jung Pyo

AU - Quang Dao, Pham Duy

AU - Yoon, Nam Sik

AU - Cho, Chan Sik

PY - 2021/6/17

Y1 - 2021/6/17

N2 - A class of trinuclear imidazole-fused hybrid scaffolds was constructed by the reaction of 2-(2-bromoaryl)- and 2-(2-bromovinyl)imidazoles with 2-aminobenzimidazoles as building blocks in the presence of a base under microwave irradiation. A nucleophilic aromatic substitution followed by cyclization is proposed as a reaction pathway of this green process.

AB - A class of trinuclear imidazole-fused hybrid scaffolds was constructed by the reaction of 2-(2-bromoaryl)- and 2-(2-bromovinyl)imidazoles with 2-aminobenzimidazoles as building blocks in the presence of a base under microwave irradiation. A nucleophilic aromatic substitution followed by cyclization is proposed as a reaction pathway of this green process.

UR - https://www.scopus.com/pages/publications/85108894736

U2 - 10.1039/d1ra04396j

DO - 10.1039/d1ra04396j

M3 - Article

AN - SCOPUS:85108894736

SN - 2046-2069

VL - 11

SP - 21367

EP - 21374

JO - RSC Advances

JF - RSC Advances

IS - 35

ER -

Microwave-assisted green construction of imidazole-fused hybrid scaffolds using 2-aminobenzimidazoles as building blocks

Abstract

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