Microwave-Assisted Synthesis of Benzo[4,5]imidazo[1,2- a ]pyrimidines from β-Bromo-α,β-unsaturated Aldehydes and 2-Aminobenzimidazoles

Son Long Ho, Pham Duy Quang Dao, Chan Sik Cho

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

β-Bromo-α,β-unsaturated aldehydes react with 2-aminobenzimidazoles by microwave irradiation in the presence of a base and magnesium sulfate to give the corresponding benzo[4,5]imidazo[1,2- a ]pyrimidines in moderate to good yields.

Original languageEnglish
Pages (from-to)1811-1815
Number of pages5
JournalSynlett
Volume28
Issue number14
DOIs
StatePublished - 1 Sep 2017

Keywords

  • aldehydes
  • coupling
  • cyclization
  • fused-ring systems
  • heterocycles

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